Fundermental examination about support capability of dental implants at the bone developed by the maxillary sinus lift

上颌窦提升骨种植牙支撑能力的基础研究

• 批准号: 11672007
• 负责人: MANABE Masato
• 金额: $ 2.24万
• 依托单位: Showa University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 1999
• 资助国家: 日本
• 起止时间: 1999 至 2000
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-11672007/
• 关键词: maxillary sinus lift; Frontal sinus; Autogenous bone; Hydroxiaptite; Tourue test; Titun implant; ハイドロキシアバタイト

The present study investigated the properties of bone tissue formed using various graft materials in maxillary sinus lift and elevation procedures. Newly formed bone was assessed in terms of viability as a supporting matrix for implants (mechanical properties) and histological affinity to implant bodies.After shaving the rostral region of 4 Beagle dogs, a skin incision was made and a mucoperiosteal flap was created. The anterior walls of the frontal sinus on both sides were then exposed and an electrical dental engine was used to create openings measuring approximately 10 × 20 mm. The sinus membrane was elevated carefully to avoid tearing and bone grafting materials packed tightly into the space. The grafting materials were divided into 4 groups: Group 1, autogenous bone harvested from the mandible and ground into small pieces; Group 2, non-resorbable HA; Group 3, resorbable HA; and Group 4, autogenous bone mixed with HA. Each grafting material was placed in 2 separate locations in each of the experimental animals. Six months after the operation, tissue samples from the grafted sites were collected by trephination in order to prepare ^histological samples and 2 titanium implants were inserted into each of the grafted sites. Six months after placement, torque tests on the implants were conducted. Polished demineralized sections were also prepared in order to examine the differences in osseous tissue formed by the 4 bone grafting materials.The autogenous bone graft group, the autogenous bone graft+HA group and the non-resorbable HA group gave torque values of 45N-cm, 41N-cm and 28N-cm, respectively. The torque value of the non-resorbable HA group was significantly lower in comparison to the two autogenous bone groups. The small number of test samples and the necessity to ensure consistency in the thickness of the cortical bone at the implant placement sites are factors that must be addressed in follow-up studies.

本研究调查了上颌窦提升和提升手术中使用各种移植材料形成的骨组织的特性。新形成的骨作为种植体的支持基质（机械性能）和组织学亲和力的可行性方面进行了评估植入bodies.After剃4比格犬的嘴部区域，皮肤切口和粘骨膜瓣创建。然后暴露两侧额窦的前壁，使用电动牙科引擎创建约10 × 20 mm的开口。小心抬高窦膜以避免撕裂，并将骨移植材料紧密填充到间隙中。将移植材料分为4组：第1组，从下颌骨采集并研磨成小块的自体骨;第2组，不可吸收HA;第3组，可吸收HA;第4组，自体骨与HA混合。将每种移植材料置于每只实验动物的2个单独位置。术后6个月，通过环钻术从移植部位收集组织样本，以制备组织学样本，并将2个钛植入物插入每个移植部位。植入后6个月，对植入物进行扭矩测试。制备抛光脱矿切片，观察4种植骨材料形成骨组织的差异，自体骨移植组、自体骨移植+HA组和不可吸收HA组的扭矩值分别为45 N-cm、41 N-cm和28 N-cm。不可吸收HA组的扭矩值显著低于两个自体骨组。试验样本数量少以及必须确保种植体放置部位皮质骨厚度的一致性是随访研究中必须解决的因素。