From trash to treasure: engineering waste carbon utilisation in yeast

变废为宝：工程废弃物碳在酵母中的利用

• 批准号: DP220100474
• 负责人: Dr Thomas Williams
• 金额: $ 35.65万
• 依托单位: Macquarie University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2022
• 资助国家: 澳大利亚
• 起止时间: 2022-08-01 至 2025-07-31
• 项目状态: 未结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP220100474
• 关键词: trash; treasure; engineering; waste; carbon

This project aims to engineer yeast to convert carbon dioxide- and methane-derived methanol into sustainable chemicals, foods, and pharmaceuticals. This project expects to generate new design principles for methanol metabolism by using the innovative approach of laboratory evolution along with state-of-the-art bio-engineering capabilities at Macquarie University and The University of Queensland. Expected outcomes of this project include new manufacturing processes for chemicals and foods, discovery of novel metabolism in yeast, and enhanced collaboration between Australia, Denmark, and the United States. This Project will provide benefits through sustainable bio-manufacturing, new economic activity, and reduced greenhouse gas emissions.

该项目旨在改造酵母，将二氧化碳和甲烷衍生的甲醇转化为可持续的化学品，食品和药品。该项目预计将通过使用实验室进化的创新方法沿着麦考瑞大学和昆士兰州大学最先进的生物工程能力，为甲醇代谢产生新的设计原则。该项目的预期成果包括化学品和食品的新制造工艺，酵母中新代谢的发现，以及澳大利亚，丹麦和美国之间加强合作。该项目将通过可持续的生物制造，新的经济活动和减少温室气体排放来提供效益。