Quantum diffractive Nanoscale Microscopy

量子衍射纳米级显微镜

• 批准号: 530098639
• 负责人: Professor Dr. Milutin Kovacev
• 金额: --
• 依托单位: Institut des Nanosciences de Paris (INSP)
• 依托单位国家: 德国
• 项目类别: Research Grants
• 资助国家: 德国
• 项目状态: 未结题
• 来源: https://gepris.dfg.de/gepris/projekt/530098639?language=en
• 关键词: Quantum; diffractive; Nanoscale; Microscopy

The QUINS project will exploit a novel non-classical source of light at extreme wavelengths based on high harmonic generation in semiconductor to develop a correlation-based quantum microscope. The harmonic emission comes as a frequency comb of N-entangled photons with frequencies extending from the IR to the deep-UV. We will exploit entangled pairs from non-denegerated photons selected from this comb. Ultrafast control over the generated quantum states will mitigate decoherence. Controlled coherent states at extreme wavelengths for advanced quantum imaging protocols will be produced. QUINS technology will develop new routes in quantum imaging (QI) with a unique advantage of transferring the sensing and resolution benefit from one spectral range to another one. This concept will be illustrated with NIR/VIS pair microscopy that will allow sensing infected cells tissue. In the future, our quantum microscope will enable non-destructive and non-invasive imaging in biology and medicine. The advantage of quantum sensitivity is that it makes weak-field imaging possible, avoiding damage to delicate samples such as living cells. We will perform tests with cells from Medical Hospital Hanover. To achieve these goals, our French-German consortium covers a wide range of expertise ranging from ultrafast laser, attosecond science, strong field quantum theory, QI and detectors to advanced optical design. Finally, several technological breakthroughs will give rise to exploitation: 1) a quantum spectrometer demonstrator allowing us to certify entanglement between NIR and VIS harmonic photons will be realized 2) a high contrast high resolution quantum microscope will be validated on living scattering media as a proof of concept.

QUINS项目将利用基于半导体中高次谐波产生的新型极端波长非经典光源来开发基于相关性的量子显微镜。谐波发射是N纠缠光子的频率梳，频率从IR延伸到深UV。我们将利用从这个梳中选择的非退化光子的纠缠对。对所产生的量子态的超快控制将减轻退相干。将产生用于先进量子成像协议的极端波长的受控相干态。QUINS技术将开发量子成像（QI）的新途径，具有将传感和分辨率优势从一个光谱范围转移到另一个光谱范围的独特优势。这一概念将说明与NIR/维斯对显微镜，将允许感测感染的细胞组织。未来，我们的量子显微镜将在生物学和医学领域实现非破坏性和非侵入性成像。量子灵敏度的优点是它使弱场成像成为可能，避免对活细胞等精细样品造成损害。我们将使用汉诺威医疗医院的细胞进行测试。为了实现这些目标，我们的法德联合体涵盖了从超快激光、阿秒科学、强场量子理论、QI和探测器到先进光学设计的广泛专业知识。最后，几项技术突破将引起开发：1）将实现量子光谱仪演示器，使我们能够证明NIR和维斯谐波光子之间的纠缠; 2）将在活体散射介质上验证高对比度高分辨率量子显微镜，作为概念验证。