Metabolite regulation of mitochondrial fission

这个项目旨在了解线粒体（细胞中产生能量的结构）的功能和健康是如何被脂肪分子控制的。该项目希望整合尖端技术和仪器，以产生关于脂肪分子如何与酶相互作用和影响的新知识，酶控制细胞如何维持线粒体对营养状态的反应。一个预期的目标是定义由脂肪分子调节的酶的指纹，这将引起生命科学许多分支的研究人员的极大兴趣。预期的结果和益处将是更深入地了解脂肪分子作为营养信号代谢产物，以及它们如何影响细胞代谢、生长和发育。

This project aims to understand how the function and health of mitochondria – the energy producing structures in cells - are controlled by fat molecules. The project expects to integrate cutting edge techniques and instrumentation to generate new knowledge of how fat molecules interact with, and influence, enzymes that control how cells maintain their mitochondria in response to nutrient state. An anticipated goal is to define a fingerprint for enzymes regulated by fat molecules that will be of great interest to researchers across many branches of life sciences. Expected outcomes and benefits will be deeper understanding of fat molecules as nutrient signalling metabolites, and how they influence cell metabolism, growth and development.