The Transfer Effects of Stationary Bicycle Perturbation Training on Older Adults' Cycling Skills and Behavior (BiPerAge): a Single Blind Randomized Controlled Trial

固定自行车扰动训练对老年人骑行技能和行为的传递效应 (BiPerAge)：单盲随机对照试验

• 批准号: 530457399
• 负责人: Dr. Robert Kob, since 12/2023
• 金额: --
• 依托单位: Institut für Biomedizin des Alterns
• 依托单位国家: 德国
• 项目类别: Research Grants
• 资助国家: 德国
• 项目状态: 未结题
• 来源: https://gepris.dfg.de/gepris/projekt/530457399?language=en
• 关键词: Transfer; Effects; Stationary; Bicycle; Perturbation

Regular cycling promotes health, mobility and independence into old age. However, the risk of older adults being injured or killed in a bicycle accident increases significantly due to the age-related decline of physical function (coordination, balance control). To counteract this trend, targeted cycling-related interventions for older adults with challenging balance training are urgently needed – but so far hardly feasible under “real world” conditions for safety reasons. Recently, the Perturbation Stationary Bicycle Robotics (PerStBiRo) system was developed by the Israeli project partner to provide motor learning and balance training in a seated position. It consists of a stationary bicycle mounted on a moving platform and a motor that provides unannounced perturbations. This innovative system makes it possible for the first time to simulate challenging balance loss situations while cycling under safe conditions (trainees wear a safety harness). To verify the transfer effect of cycling interventions, the German project partner established a standardized cycle course displaying traffic-related motor competences (e.g. turning left, getting on and off the bike, turning to the left side) The proposed randomised controlled trial with a duration of 36 months will primarily investigate whether training on the PerStBiRo system improves the cycling competence of older adults in daily traffic situations. We aim to enroll 127 community-dwelling persons aged 65 years and older living in the area of Nürnberg (Germany, n=70) and in Beer-Sheva region (Israel, n=57) who 1) feel unsteadiness while cycling or uptaking cycling after a long break and 2) have objectively measured unsteadiness while cycling (≥3 errors in cycle course performance). Participants will be randomly assigned to either the intervention group (PerTSBR – training on PerStBiRo system with pertubations) or the active control group (TSBR – training on PerStBiRo system without pertubations) with a ratio of 1:1, stratified by sex and study center. The cycling competence as primary outcome will be tested single blinded in a standardized cycle course prior (T0) and after (T1) the 3 months intervention period, which consists of variant tasks requiring motor skills related to traffic situations in daily life (e.g. riding curves, mounting/dismounting, turning to the left side). To investigate the primary objective, regression analyses with difference of errors in the cycle course [relative difference (T1-T0)/T0] as dependent variable and group (PerTSBR vs TSBR) as independent variable adjusted for sex and study center will be performed. Furthermore, we will explore on a secondary level whether the PerTSBR-training leads to long-term effects (8 months) on cycling competence and whether psychological parameters are affected by the intervention.

定期骑自行车促进健康，流动性和独立性到老年。然而，老年人在自行车事故中受伤或死亡的风险显著增加，这是由于与年龄相关的身体功能（协调，平衡控制）下降。为了应对这一趋势，迫切需要针对具有挑战性的平衡训练的老年人进行有针对性的自行车相关干预-但出于安全原因，到目前为止在“真实的世界”条件下几乎不可行。最近，以色列项目合作伙伴开发了扰动固定自行车机器人（PerStBiRo）系统，以提供坐姿运动学习和平衡训练。它由一个固定在移动平台上的自行车和一个提供突然扰动的电机组成。这一创新系统首次实现了在安全条件下（学员佩戴安全带）骑行时模拟具有挑战性的失去平衡情况。为了验证骑自行车干预的转移效果，德国项目合作伙伴建立了一个标准化的自行车课程，展示与交通相关的运动能力（例如左转、上下车、（转左）这项为期36个月的随机对照试验将主要研究PerStBiRo系统的训练是否能提高老年人在日常交通中的自行车能力situations.我们的目标是招募127名居住在纽伦堡地区（德国，n=70）和Beer-Sheva地区（以色列，n=57）的65岁及以上的社区居民，他们1）在骑自行车或长时间休息后骑自行车时感到不稳定，2）在骑自行车时客观测量了不稳定（自行车课程表现中≥3次错误）。受试者将按1：1的比例随机分配至干预组（PerTSBR -在PerStBiRo系统上进行培训，并进行扰动）或活性对照组（TSBR -在PerStBiRo系统上进行培训，但不进行扰动），并按性别和研究中心分层。 在3个月干预期之前（T0）和之后（T1），将在标准化循环课程中对作为主要结局的骑车能力进行单盲测试，其中包括需要与日常生活中的交通情况相关的运动技能的各种任务（例如，骑曲线、骑/骑自行车、向左转弯）。为了研究主要目的，将进行回归分析，以周期过程中的误差差异[相对差异（T1-T0）/T0]作为因变量，以组（PerTSBR vs TSBR）作为自变量，调整性别和研究中心。此外，我们将探讨在二级是否PerTSBR训练导致骑自行车能力的长期影响（8个月），以及心理参数是否受到干预。