Efficacy of care and treatment for emotional dysfunctions of drug abusers ; consideration of psyche-biological aspects.

目的：探讨药物滥用者的生理、心理和精神功能障碍之间的关系。方法：对日本长期专门为药物滥用者设立的戒毒康复中心(DARC)的51名药物滥用者的心理特征进行评估。为了进行评估，我们使用了以下测量方法：生物学方面的MRI、WCST、VFT和BVRT；精神/心理方面的PANSS和POMS(情绪状态简档)；精神方面的PIL(生活目的测试)；成瘾相关问题的ASI和SDS(依赖严重程度量表)。结果与结论有机溶剂滥用史长的受试者普遍表现出较差的认知能力。然而，其中禁欲时间越长的受试者表现出更高的认知表现和更低的PIL得分。研究结果表明，随着认知功能的恢复，一些施虐者可能会意识到自己的无能为力，这可能会导致精神上的削弱。

Objective : The purpose of this study is to examine the relationships between bio-psychological and spiritual aspects of dysfunctions observed in substance abusers.Methods : We evaluated characteristics of 51 substance abusers residing in DARC(Drug Addiction Rehabilitation Center), a long term residential facility specialized for abusers in Japan. To evaluate, we used following measures, MRI, WCST, VFT and BVRT for biological aspects ; PANSS and POMS (Profile of Mood States) for psychiatric/psychological aspects; PIL(Purpose in Life Test) for spiritual aspects ; ASI and SDS(Severity of Dependence Scale) for addiction-related problems. Results and Conclusions^ The subjects with long history of organic solvent abuse generally showed poor cognitive performance. Among them, however, the subjects with longer abstinence period showed higher cognitive performance and lower PIL scores. The results suggest that, with recovery of cognitive functions, some abusers may become conscious of their 'powerlessness' which could lead to a weakening of spirituality.