Anatomical Study of Human Autonomic Nervous System and Lymphatic System with Whole-mount Staining

人体自主神经系统和淋巴系统的整体染色解剖研究

• 批准号: 12670024
• 负责人: MURAKAMI Gen
• 金额: $ 1.86万
• 依托单位: Sapporo Medical University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2000
• 资助国家: 日本
• 起止时间: 2000 至 2002
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-12670024/
• 关键词: Autonomic nervous system; Lymphatic system; Thoracic duct; Uterus; Cardinal ligament; Pelvic splanchnic nerve; Celiac plexus; Regional anatomy; Whole-mount染色; 骨盤内臓神経; 広汎子宮全摘出術; wholi-mount染色; 膵頭後部リンパ節; 総肝動脈幹リンパ節; 大動脈周囲リンパ節; whole-mount染色

(1) Lymphatics in and around the Celiac Plexus (2000-2001) : We dissected postmortem-treated cadaveric specimens and examined (i) relationship between the celiac plexus and the intestinal trunk, and (ii) lymphatic collecting vessels originated from the nodes on the posterior surface of the pancreatic head (No.13) and along the common hepatic artery (No.8) into the nodes around the abdominal aorta (No.16). We also examined the lymphatic vessels and nodes around the celiac plexus with semi-serial sections of the human fetuses' abdominal viscera. These results support the reliability of (i) the extended D2 lymphadenectomy for curative cancer surgery in the pancreaticoduodenal region, and (ii) biopsy of the group 16a2-inter node, which often received afferents from the celiac plexus and diaphragmatic crus.(2) Autonomic Nerve in the Cardinal Ligament (2002) : A combination of routine dissection, fresh cadaver dissection and in situ sectional anatomy revealed that : (i) the cardinal ligament (CL) did not contain the pelvic splanchnic nerve (PSN) ; (ii) a well-defined fascial structure existed in the bottom or dorsal margin of the CL area; and (iii) the pelvic plexus was separated from vascular components of the CL. The present results provide a new perspective for nerve-sparing radical hysterectomy with extensive lateral parametrial dissection of the CL.

(1)腹腔丛内和周围的淋巴管（2000-2001年）：我们解剖了死后处理的尸体标本，并检查了（i）腹腔神经丛与肠干的关系，以及（ii）起源于胰头后表面上的淋巴结的淋巴收集管（No.13）和沿着肝总动脉（No.8）进入腹主动脉周围结节（No.16）。我们还观察了腹腔神经丛周围的淋巴管和淋巴结与半连续切片的人胎儿的腹部脏器。这些结果支持（i）扩大D2淋巴结切除术用于胰十二指肠区域癌症根治性手术的可靠性，以及（ii）16 a2组-淋巴结间活检的可靠性，其经常接受来自腹腔神经丛和神经丛的传入。(2)主韧带内的自主神经（2002）：结合常规解剖、新鲜尸体解剖和原位断层解剖发现：（i）主韧带（CL）不含盆内脏神经（PSN）;（ii）CL区底部或背侧缘存在明确的筋膜结构;和（iii）盆丛与CL的血管成分分离。本研究结果为保留神经的广泛子宫切除术和广泛的外侧子宫旁切除术提供了一个新的视角。

项目成果

Hirai I, et al.: "Long descending lymphatic pathway from the pancreaticoduodenal region to the para-aortic nodes"Okajimas Folia Anatomica Japnica. 77(6). 189-200 (2001)

Hirai I 等人：“从胰十二指肠区域到主动脉旁淋巴结的长下行淋巴通路”Okajimas Folia Anatomica Japnica。

Murakami G, et al.: "Last-intercalated node and direct lymphatic drainage into the thoracic duct from the thoracoabdominal viscera"The Japanese Journal of Thoracic and Cardiovascular Surgery. 50(3). 93-103 (2002)

Murakami G等人：“最后嵌入的淋巴结和从胸腹内脏到胸导管的直接淋巴引流”日本胸心血管外科杂志。

Kato T, et al.: "Does the cardinal ligament of the uterus contain a nerve that should be preserved in radical hysterectomy?"Anatomical Science International. 77(3). 161-168 (2002)

Kato T 等人：“子宫主韧带是否含有在根治性子宫切除术中应保留的神经？”国际解剖科学。

Hirai I, et al.: "Long descending lymphatic pathway from the pancreaticoduodenal region to the para-aortic nodes"Okajimas Folia Anatomica Japonica. 77(6). 189-200 (2001)

Hirai I 等人：“从胰十二指肠区域到主动脉旁淋巴结的长下行淋巴通路”Okajimas Folia Anatomica Japonica。

Murakami, et al.: "Last-intercalated node and direct lymphatic drainage into the thoracic duct from the thoracoabdominal viscera"The Japanese Journal of Thoracic and Cardiovascular Surgery. 50(3). 93-103

Murakami 等人：“最后嵌入的淋巴结和从胸腹内脏到胸导管的直接淋巴引流”日本胸心血管外科杂志。