The effect of somatosensory evoked potentials on the onset of voluntary movement

体感诱发电位对随意运动起始的影响

• 批准号: 12680036
• 负责人: ARAKI Hideo
• 金额: $ 1.92万
• 依托单位: The University of Tokushima
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2000
• 资助国家: 日本
• 起止时间: 2000 至 2001
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-12680036/
• 关键词: voluntary movement; SEPs; gating

The purpose of the study was to investigate the sequential changes of somatosensory evoked potentials (SEPs) accompanying voluntary movement, in comparison of self-voluntary movement and CNV-paradigm. The SEPs, Movement related cortical potentials and CNVs were recorded through the epoch preceding and accompanying movement of right thumb. Cerebral N20 and N18 were investigated according to the temporal relationship between the onset of movement and 7 epoch (500 msec) set by computer under the condition of stimulating the median nerve of right wrist. SEPs were recorded in 16 (experimental (1)) and 18 (experimental (2)) subjects and averaged in 7 successive epochs extending from 2.0 sec before onset of EMG to 0.5 sec after offset of EMG. The attenuation of both N20, i.e, gating, were clearly observed in epoch pre- and post-movement and was greatest in the epoch during movement, but that of N18 was not clear (experimental (1)). The change of N20 elicited by stimulating central nerve was different from that of N18. However, the difference between both components was not shown under the condition of stimulairig cutanuous (experimental (2)). From these findings, the gating is considered to be reflected the changes of afferent information processing at not central level but peripheral sites.

本研究旨在探讨自主运动时体感诱发电位（SEP）的时序性变化，并与CNV范式进行比较。记录右拇指运动前后的SEP、运动相关皮层电位和CNV。在电刺激右腕正中神经的条件下，根据计算机设定的运动起始时间与7个时相（500毫秒）的时间关系，测定脑N20和N18。在16名（实验（1））和18名（实验（2））受试者中记录SEP，并在EMG开始前2.0秒至EMG偏移后0.5秒的7个连续时间段内取平均值。N20的衰减，即门控，在运动前和运动后的时期都能清楚地观察到，并且在运动期间的时期最大，但N18的衰减不清楚（实验（1））。刺激中枢神经引起的N20的变化与N18的变化不同。然而，在皮肤刺激条件下（实验（2）），两种成分之间没有差异。由此可见，门控反映的不是中枢水平的传入信息加工的变化，而是外周部位的变化。

项目成果

Hideo Araki: "Modulations of short latency components of SEPs accompanying voluntary movements"PERSPECTIVE AND PROFILES 6th ECSS.. 787 (2001)

Hideo Araki：“伴随随意运动的 SEP 短潜伏期成分的调节”视角和概况第 6 届 ECSS.. 787 (2001)

Hideo Araki: "Modulations of short latency components of SEPs accompanying voluntary movements"PERSPECTIVE AND PROFILES 6th ECSS. 787 (2001)

Hideo Araki：“伴随随意运动的 SEP 短延迟成分的调节”视角和概况第 6 期 ECSS。

Hideo Araki: "Modulations of short latency components of SEPs accompanying"PERSPECTIVE AND PROFILES 6th ECSS. 787 (2001)

Hideo Araki：“SEP 的短延迟组件的调制伴随”视角和概要文件第 6 期 ECSS。