Metabolomics applied to emerging infectious diseases: Advancing biomarker discovery and characterising host-pathogen interaction in melioidosis and seps

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Melioidosis is an emerging disease in Australia and South-East Asia due to its association with diabetes and changing climate. The current clinical methods often fail to save the life of melioidosis patients who develop sepsis. This study will search for melioidosis metabolite biomarkers that help in rapid diagnosis and in selecting adequate treatment which is essential to reduce the mortality. Future, similar studies on other sepsis infections could improve clinical sepsis management world wide.