Control of degradation rate of biodegradable polymers (The application of corona discharge treatments)

电晕释放治疗对聚合物降解率的影响（L-乳酸） （PLA）和聚乳酸（ε-Caprolactone） （PCL）和Poly（丁二烯酸酯和双甲酸酯） （PBSA）已进行了研究，在聚合物表面上引入了含有氧的功能组，这些聚合物表面上的接触角被降解为30 - 60 °，并指示聚合物表面上的羟基含量的增加该合成退化测试被排除在外。对于两种治疗和未治疗的PLA、PCL和PBSA治疗抑郁了PLA的退化，当它促进了PCL和PBSATHe在微生物之间的亲和力下降时（一般性细菌， actinomycetes，Fungi）和聚合物表面也被一部电影估计了-接触方法：结果显示，治疗减少了PLA对乳酸菌的亲和力，以产生由日冕产生的抗细菌活性。在对照组上的留置治疗，冠状治疗增加了PCL ~和PBSA Especially， Aspergillus快速吸收到治疗表面，并对PCL和PBSA脂质的吸收有一个重要的退化活动（来自Aspergillus sp）在聚合物表面上也增加了退化到几个星期，自然抗细菌物质的退化，其中从日本horseradish中提取出来，在PCL和PBSA电影《Sinigrin》上张贴（从日本马Radish提取）涂覆的PCL和PBSA薄膜成功地被降级了3周，然后立即降级了PLA/淀粉混合物被涂覆了纯PLA和PCL也是由一种传统的涂层方法制成的，以控制降级率涂层的降级率被降级了2 - 4周。在他们被直接贬低之后

Effects of corona discharge treatment on the degradation rate of poly (L-lactic acid) (PLA) and Poly(ε-caprolactone) (PCL) and Poly(butylenesuccinate・adipate) (PBSA) have been investigated The treatment introduced oxygen containing functional groups onto the polymer surfaces The contact angles of these polymers decreased by 30〜60゜ indicating an increase in hydrophilicity on the polymer surfaces The composting degradation tests were carred out for both treated and untreated PLA, PCL and PBSA The treatment depressed the degradation of PLA, while it promoted the degradation of PCL and PBSAThe affinity between microorganisms (general bacteria, actinomycetes, fungi) and the polymer surfaces have also been estimated by a film-contacting method The results showed that the treatment decreased the affinity for PLA due to the production of lactic acid having antibacterial activity by the corona discharge treatment On the contrary, the corona treatment increased the affinity for PCL ~and PBSA Especially, Aspergillus sp rapidly adsorbed to the treated surfaces and has a significant degradation activity for PCL and PBSA The adsorption of lipase (from Aspergillus sp) onto the polymer surface was also increasedTo depress the degradation for several weeks, natural antibacterial substance, which was extracted from Japanese horseradish, was oated on the PCL and PBSA films The sinigrin (extracted from Japanese horse-radish) coated PCL and PBSA films were successfully depressed the degradation for 3 weeks, and then degraded immediately The PLA/starch blends coated with pure PLA and PCL were also made by a conventional coating method to control the degradation rate The degradations of the coated blends were depressed for 2〜4 weeks, after that they degraded immediately