权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

Measurements of friction in degenerated joints by a robotic arm

通过机械臂测量退化关节的摩擦力

基本信息

批准号：
12680842
负责人：
MABUCHI Kiyoshi
金额：
$ 2.05万
依托单位：
Kitasato University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
2000
资助国家：
日本
起止时间：
2000 至 2001
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-12680842/
关键词：
start-up friction robotic arm osteoarthritis ACL desmotomy hyaluronic acid joint lubrication biotribology 前十字靱帯

项目摘要

We estimated the lubrication ability of rabbit stifles that were degenerated by the abrasion of the surface layer papain injection and desmotomy of anterior cruciate ligament (ACL), respectively. Furthermore we estimated the extent to which the joint lubricating ability is restored by the addition of hyaluronic acid (HA). Joint friction as a parameter of the lubrication ability was measured by a system that was designed so a commercially available robotic arm using a universal force sensor. The force control by the loop of the robotic arm and the force sensor made the femoral condyle slide smoothly on the tibial plateau. The start-up coefficient of friction in the rabbit stifle was measured after some different periods of stationary load of 10 N. We repeated the measurements after the injection of the solution of0.1 % hyaluronic acid into the articular cartilage.We used adult Japanese white rabbits to make the degenerated stifles. We used 5 abrasion models, 9 papain injection models, and 3 ACL desmotomy models.At all three models, the average coefficient of friction significantly increased with loading duration. When fading duration surpassed 600 s, the average coefficient of friction of degenerated stifles was twice as lame as that of the control stifles. At the 150 s loading duration, the average coefficient of friction of the ACL desmotomy models was highest among these three. Followed in order by those of the papain injection models and the abrasion models.The degeneration level of cartilage appeared to correlate well with lubrication ability at 150 s loading duration. Additionally, the injection of HA recovered the value of coefficient of friction to the range about 0.1 in the models of abrasion and ACL desmotomy models.

我们分别用木瓜蛋白酶注射和前交叉韧带切开术对磨损表层的兔膝关节进行了润滑性能的评估。此外，我们估计了加入透明质酸（HA）后关节润滑能力恢复的程度。关节摩擦作为润滑能力的一个参数，通过一个系统来测量，该系统是根据市售机械臂设计的，使用通用力传感器。通过机械臂环和力传感器的力控制，使股骨髁在胫骨平台上平稳滑动。在不同时间的10 n静载后，测量兔膝关节的启动摩擦系数，并在关节软骨内注射0.1%透明质酸溶液后重复测量。我们用成年日本大白兔制作退化性窒息。我们采用5个磨损模型，9个木瓜蛋白酶注射模型，3个ACL粘连切开术模型。在所有三种模型中，平均摩擦系数随加载时间的延长而显著增加。当衰退时间超过600s时，退化后的平均摩擦系数是对照的2倍。加载时间为150 s时，前交叉韧带切断术模型的平均摩擦系数最高。其次是木瓜蛋白酶注射模型和磨损模型。加载时间为150 s时，软骨退变程度与润滑能力密切相关。此外，注射HA后，磨损模型和前交叉韧带切开术模型的摩擦系数恢复到0.1左右。