Basic Research on Artificial Muscle using Ion Polymer Metal Compound

使用离子聚合物金属化合物的人造肌肉的基础研究

• 批准号: 12680852
• 负责人: IKADA Yoshito
• 金额: $ 2.3万
• 依托单位: Suzuka University of Medical Science
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2000
• 资助国家: 日本
• 起止时间: 2000 至 2003
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-12680852/
• 关键词: Artificial Muscle; Electroconductive Polymer; Sensor; Biomaterial; Polymer Electrolyte Membrane; Actuator; Graft; Isometric Tension; ポリマー; 人工心筋; 生体適合性; 電解質膜; 医療器具

A prototype active graft was fabricated using solid polymer electrolyte membrane-Gold (SPM-Gold). SPM-GOLD graft was prepared by first heat-molding Nafion R-1100 resin into a half-pipe shape membrane. In separate preparations, a flat SPM-GOLD membrane was made from Nafion resin with preset thickness of 200-1000 μm. Isometric tension of SPM-GOLD membrane of varied width, length and thickness was measured with an isometric transducer (Ninon Kohden).Isometric tension increased by 6.7 times at 800 μm as compared to the 200 μm membrane at 100 mA while this ratio decreased as larger current was applied. For example, at 100 mA, the tension is proportional to the power of 1.4 of the thickness, i.e., F=0.000545h^<1.4> at 200 mA, it is the power of 0.98 ; Fe.0.0121h^<0.98>. Tension, as measured by force in gram of force (gf) increased with increased current of up to 300 mA and subsequently flattened out, but continued to increase up to 500 mA.Similarly, tension increased as the width of the membrane increased but not much change was observed with increased length of the membrane.Generated tension in isometric measurements increased with the thickness to a degree that enables the use of the graft for airway assistance device and possibly for active aorta graft.

利用固体聚合物电解质膜-金(SPM-Gold)制备了活性接枝物的原型。首先将Nafion R-1100树脂热模压成半管状膜，制备了SPM-Au接枝物。在不同的制备方法中，用预置厚度为200~1000μm的Nafion树脂制成平坦的SPM-金膜，用尼农-科登等距传感器测量了不同宽度、长度和厚度的SPM-金膜的等轴测张力，800μm时的等轴张力是100 mA时200μm膜的6.7倍，但随着电流的增大，这一比率下降。例如，在100 Ma时，张力与厚度的1.4次方成正比，即在200 Ma时，F=0.000545h^&lt；1.4；是0.98；Fe.0.0121h^；0.98的幂。张力，以力的克数(Gf)为单位，随着电流增加到300 mA而增加，随后趋于平缓，但在500 mA时继续增加。同样，张力随着膜的宽度增加而增加，但随着膜长度的增加变化不大。等长测量中产生的张力随着厚度的增加而增加，从而使移植物能够用于呼吸道辅助装置和可能的主动主动脉移植物。

项目成果

T.Ihara, T.Nakamura, T.Nakamura, Y.Ikada, K.Asaka, Na.Fujiwara, K.Oguro: "Isotonic Tension and Isometric Displacement Measurement of a Solid Polymer Electrolyte Membrane-Gold"Proceedings of The First World Congress on Biomimetics & Artificial Muscles. 1.

T.Ihara、T.Nakamura、T.Nakamura、Y.Ikada、K.Asaka、Na.Fujiwara、K.Oguro：“固体聚合物电解质膜-金的等渗张力和等长位移测量”第一届世界大会论文集

T.Ihara, T.Nakamura, Y.Ikada, K.Asaka, N.Fujiwara, K.Oguro: "Development of a prototype active bypass graft using Ion Polymer Metal Compound"Transaction of the Japanese Society of Medical and Biological Engineering. 43. 256 (2004)

T.Ihara、T.Nakamura、Y.Ikada、K.Asaka、N.Fujiwara、K.Oguro：“使用离子聚合物金属化合物开发原型活性旁路移植物”日本医学和生物工程学会会刊。

伊原正, 小黒啓介, 安積欣志, 藤原直子, 筏 義人: "イオンポリマーメタル複合体を用いたアクチュエータ駆動機構の基礎研究"日本ME学会雑誌. 第41巻特別号. (2002)

Tadashi Ihara、Keisuke Oguro、Kinshi Azumi、Naoko Fujiwara、Yoshito Kato：“使用离子聚合物金属复合材料的执行器驱动机构的基础研究”日本 ME 学会杂志第 41 卷特刊。

伊原 正, 中村太郎, 筏 義人, 小黒啓介, 安積欣志, 藤原直子: "イオンポリマーメタル複合体アクティブ人工血管の基礎研究"第43回日本ME学会大会論文集. 第42巻特別号. 256-256 (2004)

Tadashi Ihara、Taro Nakamura、Yoshito Kato、Keisuke Oguro、Kinshi Azumi、Naoko Fujiwara：“离子聚合物金属复合材料制成的活性血管移植物的基础研究”第 43 届日本 ME 学会会议论文集第 42 卷特刊。 (2004)

T.Ihara.T.Masuda.T.Nakamura, Y.Ikada, K.Asaka, N.Fujiwara, K.Oguro: "Isotonic Tension and Isometric Displacement Measurement of a Solid Polymer Electrolyte Membrane-Gold"Proceedings of the Society of Instrument & Control Engineers. (2003)

T.Ihara.T.Masuda.T.Nakamura、Y.Ikada、K.Asaka、N.Fujiwara、K.Oguro：“固体聚合物电解质膜-金的等渗张力和等长位移测量”仪器学会会议录