Eatablishment of rapid diagnosis and prevention of viral infectious disease prevalent in schools

我们开发了一种快速诊断手足口病并发呼吸道感染的方法，如腺病毒相关的游泳池热，这是学校卫生问题，肠道病毒71（EV71）相关的中枢神经感染，并对诺如病毒感染和预防进行了2年的调查。我们证实，PCR系统是非常有用的，用于快速鉴定腺病毒。游泳池介导的大规模腺病毒4型感染在日本经历了10年的停顿后发展起来，游泳池水的快速分析已经被常规地进行，我们建立了PCR系统，这有助于直接从临床标本中检测EV71。我们发现，EV71可以频繁地检测到严重的中枢神经系统感染，包括EV71相关的死亡和后遗症，这在日本，在区域流行的患者标本。这有助于早期诊断和早期战略。此外，PCR系统还有助于 关于我们 从脑脊液中检测EV71基因，其中基因检测是困难的。作为在手足口病存在时引起脑病等严重中枢神经感染的病毒，不仅EV71，而且科萨基A组6型（CA6）病毒也引起类似症状，这表明在检查时也应检测CA6病毒。此外，本研究调查国中生对风疹的认知情况。风疹可以通过疫苗预防，但是，最近初中生的接种率很低，将来可能会出现先天性风疹综合征。结果表明，学生对风疹及风疹疫苗知识了解不足，冬季中小学生易发生群体性急性胃肠炎。在许多情况下，食品是通过食品服务工作者的手被污染的。应制定预防感染的策略，如彻底洗手。我们建议在卫生间里放一个卫洗丽夜壶。少

We have developed a rapid diagnosis of hand-foot-and-mouth disease complicated by respiratory infection such as adenovirus-related swimming pool fever, which is an issue in school health, and enterovirus 71 (EV71) -related central nervous infection, and have investigated norovirus infection and prevention for 2 years. We confirmed that a PCR system was very useful for rapidly identifying adenovirus. Since swimming pool-mediated mass adenovirus type 4 infection, which developed after a 10-year pause in Japan, the rapid analysis of swimming pool water has been routinely performedWe established a PCR system, which facilitated direct detection of EV71 from clinical specimens. We showed that EV71 could be frequently detected in specimens from patients with severe central nervous infection, including EV71-related deaths and sequelae, which have been rare in Japan, during a regional prevalence. This has facilitated early diagnosis and early strategies. In addition, the PCR system has facilita … More ted detection of EV71 gene from cerebrospinal fluid, in which gene detection is difficult.As enerovirus causing severe central nervous infection such as encephalopathy in the presence of hand-foot-and-mouth disease, not only EV71 but also Coxsackie group A type 6 (CA6) virus caused similar symptoms, suggesting that CA6 virus should also be detected at examination.In addition, we surveyed knowledge about rubella in junior high school students. Rubella can be prevented with vaccine, however, the rate of vaccination has recently been low among junior high school students, and congenital rubella syndrome may develop in the future. It was shown that their knowledge about rubella and rubella vaccine was insufficient.In elementary and junior high schools, mass acute enterogastritis frequently develops in winter. In many cases, food is contaminated via the hands of food service workers. Strategies for preventing infection, such as thoroughly washing the hands, should be established. We proposed that a Washlet chamber pot should be employed in the rest room. Less