Experimental analysis of the cause of downward progression of rigor mortis

尸僵向下进展原因的实验分析

• 批准号: 13670417
• 负责人: KOBAYASHI Masahiko
• 金额: $ 2.11万
• 依托单位: SAITAMA MEDICAL SCHOOL (2002)The University of Tokyo (2001)
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2001
• 资助国家: 日本
• 起止时间: 2001 至 2002
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-13670417/
• 关键词: Rigor mortis; Muscle fiber types; Temperature; ^<31>P-NMR; stiffness; tension; Liquid paraffin; 筋繊維タイプ; 31P-NMR; 弾力; 骨格筋; ラット; 死後変化; NMR(核磁気共鳴装置); stiffness; ATP; クレアチンリン酸

Rigor mortis usually progresses downwards, but the cause is not known. We found that proportion of muscle fiber type affected progression of rigor mortis, and thought that the difference in the proportion between muscles is one of the causes of downward progression of rigor mortis.We use liquid paraffin to make a circumstance around muscles in dead bodies. Proportions of muscle fiber types in several kinds of rat muscles were measured with ATPase enzyme histochemistry.Postmortem changes in phosphates in the muscles were measured with ^<31>P-nuclear magnetic resonance. Creatine phosphate and ATP decreased more rapidly in red muscles than in white muscles. Postmortem changes in stiffness and rigor tension were also measured. They increased more rapidly in red muscles than in white muscles. The changes were affected by temperature.Therefore, we confirmed that rigor mortis of red muscles progressed more rapidly than that of white muscles, and that temperature affected the time course much.We thought that the effects of proportion of muscle fiber types and temperature on rigor mortis were causes of downward progression of rigor mortis in rigor mortis in human cadavers.

尸僵通常向下进展，但原因尚不清楚。我们发现肌纤维类型的比例影响尸僵的进展，并认为肌肉之间比例的差异是尸僵向下进展的原因之一。我们使用液体石蜡在尸体肌肉周围制作一个环境。用ATP酶组织化学测量几种大鼠肌肉中肌纤维类型的比例。用^ 31 P-核磁共振测量肌肉中磷酸盐的死后变化。红色肌肉中的磷酸肌酸和 ATP 下降速度比白色肌肉中更快。还测量了死后硬度和严格张力的变化。它们在红色肌肉中比在白色肌肉中增加得更快。其变化受到温度的影响。因此，我们证实红色肌肉的尸僵比白色肌肉的尸僵进展得更快，并且温度对时间进程的影响很大。我们认为肌纤维类型的比例和温度对尸僵的影响是人体尸僵中尸僵向下进展的原因。

项目成果

Masahiko Kobayashi, et al.: "Development of rigor mortis is not affected by muscle volume"Forensic Sci Int. 117. 213-219 (2001)

小林雅彦 (Masahiko Kobayashi) 等人：“尸僵的发生不受肌肉体积的影响”《法医学国际》。

Masahiko Kobayashi, et al.: "Onset of rigor mortis is earlier in red muscle than in white muscle"Int J Legal Med. 113. 240-243 (2000)

Masahiko Kobayashi 等人：“红肌中尸僵的发生早于白肌”Int J Legal Med。

M.Kobayashi et al.: "Development of rigor mortis is not affected by muscle volume"Forensic Science International. 117. 213-219 (2001)

M.Kobayashi 等人：“尸僵的发展不受肌肉体积的影响”国际法医学。

Masahiko Kobayashi: "Onset of rigor mortis is earlier in red muscle than in white muscle"Int J Legal Med. 113. 240-243 (2000)

小林正彦：“红色肌肉中尸僵的发生早于白色肌肉”Int J Legal Med。

Masahiko Kobayashi: "Development of rigor mortis is not affected by muscle volume"Forensic Sci Int. 117. 213-219 (2001)

小林正彦：“尸僵的发展不受肌肉体积的影响”法医科学国际。