EPICEMIOLOGICAL STUDY AND ESTABLISHMENT OF FOOD-DEPENDENT EXERCISE-INDUCED ANAPHYLAXIS

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FOOD-DEPENDENT EXERCISE-INCUCED ANAPHYLAXIS (FEIAN) IS CALASSIFIED AMONG PHYSICAL ALLERGY. HOWEVER, THE PATHOPHYSIOLOGY OF FEIAN REMAINS UNKNOWN AS DOES THE EPIDEMIOLOGY OF FEIAN IN THE GENERAL. THEREFORE, WE STUDIED THE EPIDEMIOLOGY OF FEIAN, ESPESICALLY ITS FREQUENCY IN JUNIOR HIGH SCHOOL AND HIGH SCHOOL STUDENTS IN JAPAN.A QUESTIONNAIRE ASKING ABOUT THE OCCURRENCE OF FEIAN IN THESE POPULATIONS WAS SENT TO ALL 145 PUBLIC JUNIOR HIGH SCHOOL NURSES IN YOKOHAMA AND 166PUBLIC HIGH SCHOOL NURSES IN KANAGAWA PREFECTURE, JAPAN.130 JUNIOR HIGH SCHOOL NURSES AND138 SCHOOL NURSES RESPONDED THE QUESTIONNAIRE, AND 13 CASES OF FEIAN (11 BOYS, 2 GIRLS) IN 76, 229 JUNIOR HIGH SCHOOL STUDENTS AND 9 CASES (6 BOYS, 3 GIRLS) IN 104,701 HIGH STUDENTS WERE REPORTED. IN ADDITION, 24 CASES OF EXERCISE-INDUCED ANAPHYLAXIS (EIAN) (12 BOYS, 12 GIRLS) IN JUNIOR HIGH SCHOOL AND 17 (9 BOYS, 8 GIRLS) WERE DETECTED.FROM THIS SURVEY, THE FREQUENCY OF FEIAN AND EIAN WAS 0.017% AND 0.034% IN JUNIOR HIGH SCHOOL AND 0.086% AND 0.016% IN HIGH SCHOOL, RESPECTIVERLY. ONLY ONE HALF OF SCHOOL NURSES HAD ANY KNOWLEDGE OF FEOAN. WE ALSO PERFORMED PROVOCATION TESTS IN 9 OF THE 22 STUDENTS WITH FEIAN AFTER OBTAINING THERIR INFORMED CONSENTS AND CONFIRMED THE DIAGNOSIS.ESTABLISHMENT OF ANIMAL MODEL OF FEIAN IS STILL ON THE WAY TO DEVELOP. NOW, WE FOUND ONE CANDIDATE OF THE ANIMAL MODEL. IT STILL KAKES A TIME TO GET THE FINAL RESULTS.THIS STUDY SHOWED THAT FEIAN AND EIAN ARE RELATIVEL Y RARE IN JUNIOR HIGH SCHOOL AND HIGH SCHOOL STUDENTS IN JAPAN. TO ACOID SERIOUS OUTCOMES AND UNNECESSARY RESTRICTIONS, IT IS IMPORTANT FOR PHYSICANS, BUT ALSO SCHOOL NURSES AND TEACHERS OF PHYSICAL EDUCATION TO BE FAMILIAR WITH THE DISEASES.