APATITE-FORMING ABILITY OF ORGANIC POLYMERS CONTAINING CARBOXY GROUP

羧甲基化的几丁质和结冷胶都含有羧基，只有在Ca(OH)_2溶液处理后才能在SBF表面形成磷灰石。不含羧基的Cardlan凝胶即使经过Ca(OH)_2处理也不形成磷灰石。通过喷嘴将海藻酸钠溶液挤压到氯化钙溶液中制备海藻酸钙纤维。构成无纺布的几丁质纤维被羧甲基化。经Ca(OH)_2处理后，两种纤维表面均形成磷灰石。Ca(OH)_2溶液处理后的纤维释放出的钙离子在纤维表面形成有利于磷灰石成核的羧基，并通过提高SBF中磷灰石的离子活度积来加速磷灰石成核。用本方法制备的磷灰石有机纤维复合材料有望作为一种柔性生物活性b- 1修复材料

Carboxymethylated chitin and gellan gum, both of which contain carboxy groups, formed an apatite on their surfaces in SBF, only after Ca(OH)_2 solution treatment. Cardlan gels containing no carboxy group did not form the apatite even after the Ca(OH)_2 treatment. Calcium alginate fibers were prepared by extruding sodium alginate solution into calcium chloride solution through a nozzle. Chitin fibers constituting a nonwoven fabric were carboxymethylated. Both of the fibers formed the apatite on their surfaces in SBF, after the Ca(OH)_2 treatment. The calcium ion released from the fibers treated with Ca(OH)_2 solution might form carboxy groups effective for the apatite nucleation on the surface of the fibers and accelerate the apatite nucleation by increasing ionic activity product of the apatite in SBF. The apatiteorganic fiber composite prepared by the present method is expected to be useful as a flexible bioactive b-one repairing material