Study of Remote early diagnosis system for malfunction of implantable artificial heart

植入式人工心脏故障远程早期诊断系统研究

• 批准号: 13680951
• 负责人: OKAMOTO Eiji
• 金额: $ 2.11万
• 依托单位: Hokkaido Tokai University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2001
• 资助国家: 日本
• 起止时间: 2001 至 2003
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-13680951/
• 关键词: Artificial Heart; Early Diagnosis; Assist pump; Adaptive Filter; Electro-stethoscope; Mobile Communications; Remote Monitoring; CAD; 遠隔医療; 移動体通信; 電子聴診システム; 異常診断

We have studied early diagnosis system for detecting symptom of malfunction of an implanted artificial heart before threatening patients' life. The early diagnosis system consists of a electro-stethoscope and a mobile computer. Sound signal generated by an artificial heart is an index of the degree of mechanical deterioration, because the sound signal is related to the condition of each mechanical components of the artificial heart. Sound data, which are detected on the surface of the body of a discharged patient in whom a TAK has been implanted. are transmitted to a host computer in a hospital via a mobile telephone (PHS).The early diagnosis system has two type of unique filters 1) an optimum frequency characteristics of low-pass filter based on simulating sound transmission characteristics of tissue, and 2) adaptive noise canceller, in order to eliminate ambient sound signal mixed in artificial heart's sound signal. The early diagnosis system was able to detect symptom of pump malfunction in in-vivo experiment using a goat implanted an undulation pump total artificial heart. The results of this study showed that the early diagnosis system contributes to improvement in the quality of life of discharged artificial heart patients by ensuring their safety.

我们研究了一种早期诊断系统，用于在危及患者生命之前检测植入式人工心脏的故障症状。早期诊断系统由电子听诊器和移动的计算机组成。人工心脏产生的声音信号是机械退化程度的指标，因为声音信号与人工心脏的每个机械部件的状况有关。声音数据，在已植入TAK的出院患者体表检测到。通过移动的电话（PHS）传输到医院的主机上。该早期诊断系统具有两种独特的滤波器：1）基于模拟组织的声音传输特性的低通滤波器的最佳频率特性;在山羊植入波动泵型人工心脏的体内实验中，该系统能够检测到泵故障的症状。本研究的结果表明，早期诊断系统有助于提高出院人工心脏患者的生活质量，确保他们的安全。

项目成果

E Okamoto, E Iawasawa, S Suzuki, S Fukuoka, Y Mitamura: "Feasibility of a remote monitoring system for patients with a implantable left ventricular assist device using personal handy-phone system"Journal of Artificial Organs. 4. 172-179 (2001)

E Okamoto、E Iawasawa、S Suzuki、S Fukuoka、Y Mitamura：“使用个人手持电话系统对植入式左心室辅助装置患者进行远程监测系统的可行性”人工器官杂志。

E.Okamoto: "FEM & CAD/CAM technology applied for design of implantable LVAD blood pump"Journal of Congestive Heart Failure and Circulatory Support. 1(4). 391-398 (2001)

E.Okamoto：“有限元法

E.Okamoto, T.Inoue, K.Watanabe, T, Hashimoto, E.Iwazawa, Y.Abe, T.Chinzei, T.Isoyama, S.Kobayashi, I.Saito, F.Sato, H.Matsuki, K.Imachi, Y.Mitamura: "Development of an implantable high-energy and compact battery system for artificial heart"Artificial Orga

E.Okamoto、T.Inoue、K.Watanabe、T、Hashimoto、E.Iwazawa、Y.Abe、T.Chinzei、T.Isoyama、S.Kobayashi、I.Saito、F.Sato、H.Matsuki、K.

Eiji Okamoto, Takuya Hashimoto, Taku Inoue, Yoshinori Mitamura.: "Blood compatible design of a pulsatile blood pump using comptational fluid dynamics and computer-aided design and manufacturing technology"Artificial Organs. 27(1). 61-67 (2003)

Eiji Okamoto、Takuy​​a Hashimoto、Taku Inoue、Yoshinori Mitamura。：“使用计算流体动力学和计算机辅助设计和制造技术的脉动血泵的血液相容性设计”人工器官。

岩澤英智: "電子聴診システムを用いた体内埋込型人工心臓発生音の計測"電子情報通信学会技術報告MBE. 2001・96. 89-93 (2001)

Hidetomo Iwasawa：“使用电子听诊系统测量植入式人工心脏产生的声音”IEICE 技术报告 MBE 2001/93 (2001)。