Evaluation of Degradation Characteristics of Ni-Ti Super-Elastic Alloy in Quasi-Human Body Environment and Improvement of its Bio-Compatibility by Surface Modification

在过去的几年里，生物医学材料的需求随着年龄社会的形成而增加，与低出生率的共同疾病患者年龄结合在一起。生物材料是指专门为人体的受损或受损部分而设计的材料的修复、重建和替换。生物材料必须具有可靠性，以便在预期的时间内保持人体的功能，而且它们也必须显示出与人体的生物兼容性。镍钛形状存储器合金（镍钛合金）具有独特的机械性能，具有形状存储器效应和具有良好的耐腐蚀性的超弹性。由于这一原因Ni-Ti合金预计将用于生物医学领域的植入物材料。However，人体环境和镍钛合金的生物相容性的退化特征并没有得到充分的检验。本研究的目的是评估体外腐蚀和磨损腐蚀抵抗力，细胞通 ... More 生物材料的耐受性和生物学反应，特别是通过体内动物植入分析和改进Ni-Ti合金对腐蚀性的改进，因此，作者已经从下面的视点点接受了各种研究。（1）质量人体环境中生物材料的降解特性的评估和生物材料的生物反应的评估;（2）通过各种表面修改生活环境中镍钛超弹性合金的改进;（3）建立具有更好的生物相容性结果的材料系统，通过分类纳入后续项目。对腐蚀退化行为和生物相容性的评估;对镍钛形状记忆合金的镍钛形状记忆合金的兼容性的评估;对有色人种周围组织中活身体中各种物质物质的腐蚀和磨损特征的评估;对有色人种-人体环境中的老化和磨损特征的评估;对镍钛形状记忆合金中的其他元素对老化和磨损特征的影响。评估生物材料钛合金对腐蚀的抵抗力和生物相容的钙磷酸薄膜使用电化学方法形成/Quasi-人体中生物陶瓷的接触腐蚀特征

In recent years, the demand for a biomedical material is increasing with the formation of the aged society with a low birth rate, together with the lowering in joint disease patient's age. Biomaterials mean the materials specially designed for the repair, reconstruction, and replacement of diseased or damaged part of human-body. Bio materials must have the reliability to hold their functions during expected time in the human body and also they have to show bio-compatibility to the living body. Nickel-titanium shape memory alloy(Ni-Ti alloy) has unique mechanical properties such as shape memory effect and super elasticity along with good wear and corrosion resistances. For this reason Ni-Ti alloy is expected to use as implants material in the biomedical field. However, the degradation characteristics in living body environment and the biocompatibility of Ni-Ti alloy is not fully examined. The purpose of this research to evaluate in vitro corrosion and wear-corrosion resistances, cytocom … More patibility and the biological response of bio materials, especially to evaluate inflammatory response by in vivo animal implantation assays and improvement of corrosion resistance for Ni-Ti alloy by various surface modifications.Therefore, authors have been conducted various researches from the following view points.(1)Evaluations of degradation characteristics of bio materials in quasi-human body environment and the biological response of bio materials(2)Improvement of degradation characteristics of Ni-Ti super-elastic alloy in living body environment by various surface modifications(3)Establishment of materials systems with better bio-compatibilityResults obtained are summarized through categorizing into following items.・Evaluation of Corrosion Degradation Behavior and Bio-compatibility and of Ni-Ti Shape Memory Alloy・Evaluation of Compatibility of Nickel-Titanium Shape Memory Alloy with Femur Surrounding Tissue・Corrosion and Wear Corrosion Characteristics of Various Substitutive-Materials for Living Body in Quasi-Human Body Environment・Effects of Additional Elements on Erosion and Wear Characteristics in Ni-Ti Shape Memory Alloy・Evaluation of Corrosion Resistance of Biomaterial Titanium Alloy and Formation of Biocompatible Calcium Phosphate Thin Film Using Electrochemical Method・Contact Corrosion Fatigue of Bio-Ceramics in Quasi-human Body Environment Less