Clinical use of a robot with an automatic chasing capability of the target for MR image guided surgery
Clinical use of a robot with an automatic chasing capability of the target for MR image guided surgery
批准号:
17300171
负责人:
MORIKAWA Shigehiro
金额:
$9.77万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2005
资助国家:
日本
项目状态:
已结题
起止时间:
2005 至 2007
中文摘要
本研究项目的目的是利用便携式机器人在临床笼中进行核磁共振图像引导的肝脏肿瘤微波消融。我们开发了一个具有2个光学角度传感器和3个超声波马达的核磁共振兼容机器人,该机器人利用远程运动中心约束自动追逐预定的目标点。该机器人在强磁场下正常工作,即使在超声电机运动过程中也不干扰磁共振成像。机器人控制的图像中心位置误差小于2尼姑,虚拟针长为15 cm。为了临床应用,我们在手持式角度传感器的光纤上制备了连接器。因此,末端执行器可以从主要部件中分离出来进行灭菌。为了患者的安全,在机器人的垂直杆上安装了一个由铰链和楔子组成的机械保险丝。当施加在手臂上的力超过预设阈值时,关节被释放,手臂上升。还增加了棘轮机构,使机械臂保持在抬起的位置。在这种情况下,机械臂不能接触病人。为增加安全机制,还准备了一个电气关闭开关。我校伦理委员会批准了该机器人的临床应用。在安全问题清除后,对志愿者反复进行模拟研究。并对导航软件进行了优化,以适应临床使用。最后将该机器人应用于2例肝脏肿瘤MR引导微波消融的临床。该过程成功安全地完成,机器人辅助在此过程中被发现是有用的。
英文摘要
The objective of this research project is the utilization of a portable robot for MR-image-guided microwave ablation of liver tumors in clinical cages. We have developed an MR-compatible robot having 2 optical angle sensors and 3 ultrasonic motors, which automatically chases the predefined target point using remote-center-of-motion constraint. This robot properly worked in the strong magnetic field and did not interfere with MR imaging even during the movement of the ultrasonic motors. The error of the image center position controlled by the robot was less than 2 nun with a virtual needle length of 15 cm. For clinical use, connecters were prepared on the optic fiber of the angle sensors of the hand-piece. Accordingly, the end effecter could be separated from the main parts for the sterilization. For the safety of patients, a mechanical fuse, consisting of a hinge and wedge, was prepared on the vertical pole of the robot. The joint was released and the arm went up when the force to the arm exceeded the preset threshold. A ratchet mechanism was also added to keep the robot arm at the lifted position. In this situation, robot arm could not physically touch the patient. An electrical shut-down switch was also prepared for additional safety mechanism. The Ethics Committee of our university approved the clinical use of this robot. After the clearance of safety issue, simulation studies were repeatedly conducted with volunteers. and navigation software was optimized for the clinical use. Finally this robot was used in 2 clinical cases for MR guided microwave ablation of liver tumors. The procedures were successfully and safely accomplished, and the robot assistance in this procedure was found to be useful.
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Disruption of erythrocytes distinguishes fixed cells/tissues from viable cells/tissues following microwave coagulation therapy
微波凝固治疗后红细胞的破坏可区分固定细胞/组织与活细胞/组织
DOI:
--
发表时间:
2005
期刊:
Digest Dis Sci 50(7)
影响因子:
--
作者:
[Yamaguchi, Mulcaisho, K., Yamamoto, H., Shiomi, H., Kurumi, V., Sugihara, H., Tani, T]
通讯作者:
T
MRI-Compatible Manipulator for Ablation Therapy for Liver Tumors Using Synergistic Virtual Remote-Center-of-Motion Control
使用协同虚拟远程运动中心控制的 MRI 兼容机械臂用于肝脏肿瘤消融治疗
DOI:
--
发表时间:
期刊:
J Magn Reson Imaging(掲載確定)
影响因子:
--
作者:
[Hata N, Tokuda J, Huxwitz S, Morikawa S]
通讯作者:
Morikawa S
DOI:
--
发表时间:
2006
期刊:
影响因子:
--
作者:
[Morikawa S, Murakami K. Naka S, Iiurumi Y, Moritan Z, Inubushi T, Nakakubo T, LTmihuari, Haque HA, Hata N., Morikawa S.]
通讯作者:
Morikawa S.
MR guided microwave surgery for liver tumor with MR gradient-basedtracking system.
使用基于 MR 梯度的跟踪系统进行 MR 引导的肝脏肿瘤微波手术。
DOI:
--
发表时间:
2006
期刊:
影响因子:
--
作者:
[Naka S, Kurumi Y, Morikawa S, Shiomi H, Tani T.]
通讯作者:
Tani T.
Intraluminal image navigation with a micro-sensor of MR gradient based tracking system.
使用基于 MR 梯度的跟踪系统的微传感器进行腔内图像导航。
DOI:
--
发表时间:
2006
期刊:
影响因子:
--
作者:
[Murakami K, Naka S, Demura K, Sato K, Haque HA, Shiomi H, Morikawa S, Inubushi T, Kurumi Y, Tani T.]
通讯作者:
Tani T.
共 58 条
Study for ultra-fast and highly-sensitive MR spectroscopic imaging using a high-field magnet and a high-performance gradient coil.
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批准号:23659584
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.33万
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财政年份:2011
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负责人:MORIKAWA Shigehiro
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依托单位:
Realization of Real-Time MR Image Guided Surgery Combined with High-Resolution 3D Image Navigation
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批准号:13671227
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.92万
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财政年份:2001
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负责人:MORIKAWA Shigehiro
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依托单位:
海外基金