Realization of Real-Time MR Image Guided Surgery Combined with High-Resolution 3D Image Navigation

结合高分辨率3D图像导航实现实时MR图像引导手术

• 批准号: 13671227
• 负责人: MORIKAWA Shigehiro
• 金额: $ 1.92万
• 依托单位: SHIGA UNIVERSITY OF MEDICAL SCIENCE
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2001
• 资助国家: 日本
• 起止时间: 2001 至 2002
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-13671227/
• 关键词: MR-guided surgery; minimally invasive surgery; computer-assisted surgery; Thermal therapy; MR temperature map

Real-time MR images, which are acquired every 2-3 seconds, are quite useful for image-guided surgery, but their image resolution and contrast are not always satisfactory because of the limited acquisition time. We planed to combine high resolution preoperative 3D image data with real-time MR images for surgical navigation. First, we prepared a program on the MR system to send acquired real time images and the information, of the hand-piece position for image plane control continuously. Navigation software, 3D Slicer, was obtained from Harvard, was installed in an independent computer and was customized for our purpose, We could successfully reconstruct reformatted images in the same and perpendicular planes as the real-time MR images from preoperative 3D image data and send these images to the surgeons inside immediately. Although the needle position had to be recognized in the real-time images, the reformatted images showed the target more clearly than the real-time. This system has already been used in 50 cases of microwave ablation for liver tumors and 10 neurosurgical cases. The reformatted images could also show the surrounding structures of the target, such as large vessels, and made the procedure safer. For the real-time MR images, Tl-weighted images are usually used, but any images with different contrasts, such as T2-weighte images or Gd-enhanced images could be combined as the preoperative 3D volume data. In the microwave thermocoagulation therapy of liver tumors, punctures and ablations are repeated many times. We added "FootPrinting" function in this software in order to record the individual football-shaped coagulation areas in the 3D space. This function made the procedure more accurate and easy. This system is now used in all the procedures.

每2-3秒采集一次的实时MR图像对于图像引导手术非常有用，但是由于采集时间有限，其图像分辨率和对比度并不总是令人满意。我们计划将联合收割机高分辨率术前3D图像数据与实时MR图像结合用于手术导航。首先，我们在MR系统上准备了一个程序，以连续发送采集的真实的时间图像和图像平面控制的手柄位置信息。导航软件3D Slicer是从哈佛获得的，安装在一台独立的计算机上，并根据我们的目的进行定制，我们可以成功地在与术前3D图像数据的实时MR图像相同和垂直的平面上重建重新格式化的图像，并立即将这些图像发送给内部的外科医生。尽管必须在实时图像中识别针位置，但重新格式化的图像比实时图像更清楚地显示了目标。该系统已用于50例肝肿瘤微波消融和10例神经外科手术。重新格式化的图像还可以显示目标的周围结构，例如大血管，并使手术更安全。对于实时MR图像，通常使用T1加权图像，但是可以将具有不同对比度的任何图像（诸如T2加权图像或Gd增强图像）组合为术前3D体积数据。在肝肿瘤的微波热凝治疗中，需要多次穿刺和消融。我们在该软件中增加了“FootPrinting”功能，以便在3D空间中记录单个足球形状的凝固区域。该功能使程序更加准确和简单。目前，该系统已用于所有程序。

项目成果

Morikawa S, Inubushi T, et al.: "Lecture Notes in Computer Science 2489、Technical developments for MR-guided microwave thermocoagulation therapy of liver tumors"Splinger. 8 (2002)

Morikawa S、Inubushi T 等人：“计算机科学讲义 2489，MR 引导的肝脏肿瘤微波热凝治疗的技术发展”Splinger 8 (2002)。

谷徹, 来見良誠, 森川茂廣: "腹部外科とナビゲーションサージャリー"手術. 56. 1451-1460 (2002)

Toru Tani、Yoshimasa Kurumi、Shigehiro Morikawa：“腹部手术和导航手术” 56. 1451-1460 (2002)。

Ishii H, Arai T, Segawa H, Morikawa S, Inubushi T, Fukuda K: "Effects of propofol on lactate accumulation and oedema formation in focal cerebral ischaemia in hyperglycaemic rats"Brit J Anaesth. 88. 412-417 (2002)

Ishii H、Arai T、Sekawa H、Morikawa S、Inubushi T、Fukuda K：“异丙酚对高血糖大鼠局灶性脑缺血中乳酸积累和水肿形成的影响”Brit J Anaesth。

Morikawa S, Inubushi T, Kurumi Y, et al.: "MR-guided microwave thermocoagulation therapy of liver tumors: initial clinical experiences using a 0.5T open MR system."Journal of Magnetic Resonance Imaging. 16. 576-583 (2002)

Morikawa S、Inubushi T、Kurumi Y 等人：“MR 引导的肝脏肿瘤微波热凝治疗：使用 0.5T 开放式 MR 系统的初步临床经验。”磁共振成像杂志。

Morikawa S, Inubushi T, Kurumi Y et al.: "New assistive devices for MR-guided microwave thermocoagulation of liver tumors."Academic Radiology. 10. 180-188 (2003)

Morikawa S、Inubushi T、Kurumi Y 等人：“用于 MR 引导的肝脏肿瘤微波热凝的新型辅助装置。”学术放射学。