Fundamental verification of pulmonary rehabilitation technique and its establishment of the significance

本文用脉冲振荡系统(IOS)研究了COPD患者呼气时呼吸阻力(RRS)的增加和呼吸电抗(XRS)的负移。阻抗的频率依赖性(ZRS)在COPD中更为显著，对呼吸周期的依赖性也较深。在这项研究的过程中，我们开发了一种新的仪器，可以在多个频率上测量RRS、XRS和ZRS，可以用来替代IOS(申请专利)。我们测量了PLB过程中的口腔内压，发现对支气管有效的正压大约在3-4cmH2O左右。本文对PLB时的脑电(EEG)进行了研究，发现α波频率上移，心率减慢。在PLB期间，我们使用喉部纤维软镜确认口咽闭合。这就解释了为什么在…期间不需要修鼻之前，我们证实了对PATI PLR进行手动胸部理疗更多的COPD患者显著减少了肺体积。在本研究期间，我们进一步证实，这种影响持续了至少3个小时。CPT后呼吸肌耗氧量减少，对递增死腔负荷的耐力时间延长。根据这些经验，我们新开发了缓解慢性呼吸系统疾病患者呼吸困难的呼吸体操“仙台市呼吸康复体操”，并已在仙台市向市民推广。我们开发了能够进行多级阻力负荷的吸气阻力装置。使用该仪器，对吸气阻力的呼吸反应被发现是对呼吸模式的反应，这些结果支持了一种呼吸训练缓解呼吸困难的历史指示。为了阐明运动中大致的供氧量，我们试图测量胸锁乳突肌(SCM)的组织氧饱和度(StO2)，并建立这些方法。COPD患者深吸气肌运动过程中SCM的血氧饱和度降低，而健康人则无明显变化。氧气供应抵消了下降的影响。在COPD患者中，我们阐明了呼吸阻力(RRS)增加，呼吸电抗(XRS)在呼气时使用脉冲振荡系统(IOS)向负方向移动。阻抗的频率依赖性(ZRS)在COPD中更为显著，对呼吸周期的依赖性也较深。在这项研究的过程中，我们开发了一种新的仪器，可以在多个频率上测量RRS、XRS和ZRS，可以用来替代IOS(申请专利)。我们测量了PLB期间的口腔内压，并得出对支气管有效的正压约为3-4cmH2O。脑电图仪$更少

In patients with COPD, we elucidated that respiratory resistance (Rrs) was increased and respiratory reactance (Xrs) was shifted toward negative direction during expiration using impulse oscillation system (IOS). Frequency dependence of impedance (Zrs) was more remarkable in COPD and those respiratory cycle dependency was also profound. In this process of this research, we developed new apparatus to measure Rrs, Xrs, and Zrs at multiple frequency that can be used as alternative to IOS (patent in application).We measured intra-mouth pressure during PLB, and found the positive pressure that is assumed to be effective for bronchus was around 3 to 4 cmH2O. Electro encephalogram (EEG) during PLB was studied, and we found up-ward slid in alfa-wave Frequency and decrease in heart rate. During PLB, we confirmed oropharyngeal closure using flexible laryngeal fiber Scope. This explain why nose clipping is unnecessary during PLRPreviously we confirmed that manual chest physiotherapy (CPT) to pati … More ents with COPD significantly reduced lung volume. In the present research period, we further Confirmed that the effects persisted for at least 3 hours. We also observed the decrease in oxygen consumption of the respiratory muscle after CPT, and the prolongation in the endurance time for the incremental dead space loading. From these experiences, we newly developed respiratory gymnastics "Sendai city respiratory rehabilitation gymnastics" for alleviation of dyspnea in patients with chronic respiratory disease, which was already introduced to citizens in Sendai city.We developed inspiratory resistance apparatus that enables multi step resistance loading. Using that machine, ventilatory response to inspiratory resistance was found to be a response of ventilatory pattern, and these results support the historical instruction about dyspnea alleviation by a kind of respiratory training.To clarify the approximate amount of oxygen supply during exercise, we tried to measure tissue oxygen saturation (StO2) at sternocleidomastoid (SCM) muscles, and established those methods. StO2 at SCM in patients with COPD decreased during deep inspiratory muscle works whereas those in healthy subjects did not. The decrease was canceled by oxygen supply. Submission of paper about these are being prepared.In patients with COPD, we elucidated that respiratory resistance (Rrs) was increased and respiratory reactance (Xrs) was shifted toward negative direction during expiration using impulse oscillation system (IOS). Frequency dependence of impedance (Zrs) was more remarkable in COPD and those respiratory cycle dependency was also profound. In this process of this research, we developed new apparatus to measure Rrs, Xrs, and Zrs at multiple frequency that can be used as alternative to IOS (patent in application).We measured intra-mouth pressure during PLB, and frnmd the positive pressure that is assumed to be eective for bronchus was around 3 to 4 cmH2O. Electro encephalogr$ Less