Development of irradiation field for neutron capture therapy using direct neutrons from compact proton accelerator
Development of irradiation field for neutron capture therapy using direct neutrons from compact proton accelerator
批准号:
17300172
负责人:
KOBAYASHI Tooru
金额:
$7.8万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2005
资助国家:
日本
项目状态:
已结题
起止时间:
2005 至 2007
中文摘要
点击翻译按钮获取中文摘要
英文摘要
We examined the characteristics of the target assembly for the direct usage of near threshold^7L i(p,n)^7Be neutrons for BNCT. We were able to clarify the following :1) We performed a parametric survey, via simulation, of the dependence of the characteristics of the BNCT irradiation field on the thickness of the lithium target. Neutron and gamma ray fluxes were determined in order to verify the usability of the irradiation fields for BNCT. We also investigated the influence of incident proton energy on the irradiation field by considering energies between 1.89MeV to 1.92MeV. The evaluation indices applied were the treatable protocol depth (TPD) and boron-dose enhancer (BDE) thickness.2) Regarding gamma ray production in the target assembly, our experiment at the HIRRAC in Hiroshima University showed that tungsten and molybdenum were better than copper and aluminum as backing materials at the proton energy of 1.9MeV. During the same experiment, solid Li with thickness of 10μm deposited … More on a W plate had exfoliated after several hours of irradiation at 150μA. It was therefore judged that solid Li is not suitable for practical use from the viewpoint of target life-time. Based on this result, we performed fundamental experiments on the potential use of thin film liquid Li target simulated by water flow formation. We confirmed that practical liquid film will be possible for a thickness of 1mm at 50mm in width and 50mm in length and a flow rate of 30m/s generated from a linear array of nozzles and flowing against a guide plate.3) The liquid Li-metal flow experiment (2005) in the IFMIF project and the remarkable achievement of the group of ANL suggested that liquid Li thin film formation is technically possible and the prospect of its practical implementation is high.As to the neutrons from the near threshold^7Li (p,n) ^7Be reaction, we are going to continue to develop a BNCT irradiation field, and will push for the future implementation of accelerator BNCT irradiation system. Less
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
登录
查看更多内容
Influence of BDE Shane and Size on the Dose Components for BNCT using the Near Threshold^7Li(p,n)^7Be Direct Neutrons
BDE Shane 和尺寸对使用近阈值^7Li(p,n)^7Be 直接中子的 BNCT 剂量分量的影响
DOI:
--
发表时间:
2005
期刊:
影响因子:
--
作者:
[M., Teraishi, T., Kobavashi, G., Bengua, K., Tanaka, Y., Nakagawa, N., Sakamotol]
通讯作者:
Sakamotol
Study on the practical conditions for Li-target thickness and Gaussian proton energies in the production of neutrons for BNCT using the near-threshold^7iLi(p,n)^7Be reaction
利用近阈值^7iLi(p,n)^7Be反应生产BNCT中子时锂靶厚度和高斯质子能量的实际条件研究
DOI:
--
发表时间:
2006
期刊:
影响因子:
--
作者:
[Tooru, Kobavashi, Gerard, Bengua, Kenichi, Tanaka, Yoshinobu, Nakagawa, Masaharu, Hoshi]
通讯作者:
Hoshi
Gaussian Proton Energy Spectrum for BNCT using Near Threshold^7Li(p,n)^7Be Neutrons
使用近阈值^7Li(p,n)^7Be 中子的 BNCT 高斯质子能谱
DOI:
--
发表时间:
2005
期刊:
Jpn. Jour. Med. Phys 3-1
影响因子:
--
作者:
[G., Bengua, T., Kobavashi, K., Tanaka, Y., Nakagawa]
通讯作者:
Nakagawa
TPD based evaluation of moderator characteristics for BNCT using 7^Li(p,n)neutrons at proton energy of 2.5 MeV
基于 TPD 的 BNCT 慢化剂特性评估,使用 7^Li(p,n) 中子,质子能量为 2.5 MeV
DOI:
--
发表时间:
2005
期刊:
Japanese Journal of Medical Physics 25(Sup.3-1)
影响因子:
--
作者:
[Tanaka, K.]
通讯作者:
K.
TPD-based evaluation of near threshold mono-energetic proton energies for the 7Li(p,n)7Beproduction of neutrons for BNCT
基于TPD的7Li(p,n)7Be生产BNCT中子的近阈值单能质子能量评估
DOI:
--
发表时间:
2006
期刊:
Physics in Medicine and Biology 51
影响因子:
--
作者:
[G. Bengua, T. Kobayashi, K. Tanaka, Y. Nakagawa, H. Unesaki]
通讯作者:
H. Unesaki
共 21 条
THE DEVELOPMENT OF A LIQUID LITHIUM NEUTRON GENERATING TARGET FOR ACCELERATOR BASED NEUTRON CAPTURE THERAPY
-
批准号:20240054
-
项目类别:Grant-in-Aid for Scientific Research (A)
-
资助金额:$32.03万
-
财政年份:2008
-
负责人:KOBAYASHI Tooru
-
依托单位:
Study on Hyper Thermal Neutron Irradiation Field for Neutron Capture Therapy
-
批准号:08458125
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$4.54万
-
财政年份:1996
-
负责人:KOBAYASHI Tooru
-
依托单位:
Study on Detectors for On-line Measurement and estimation of absorbed energy using SPECT system in Neutron Capture Therapy
-
批准号:07558186
-
项目类别:Grant-in-Aid for Scientific Research (A)
-
资助金额:$3.52万
-
财政年份:1995
-
负责人:KOBAYASHI Tooru
-
依托单位:
海外基金