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Development of a gas-scintillator detector and measurements of medical nuclear data at HIMAC

HIMAC 开发气体闪烁体探测器并测量医学核数据

基本信息

批准号：
17360460
负责人：
UOZUMI Yusuke
金额：
$ 5.4万
依托单位：
Kyushu University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (B)
财政年份：
2005
资助国家：
日本
起止时间：
2005 至 2007
项目状态：
已结题

项目摘要

Particulate radiation therapy is one of the most effective treatments for variety of cancers, because it offers a high possibility to cure serious cancer with high QOL To suppress side effects effectively, it is required to develop a method of advanced treatment planning based on accurate estimate of radiation dose. Nuclear fragments play a key role in destructing DNA, hence nuclear data are important quantity to realize the dose estimation system. Since there are difficulties in measuring these data, which have a very high linear energy transfers, it is necessary to develop a new detector system. Therefore, we developed a scintillator detector system and applied it to nuclear data measurements at HIMAC, NIRS. Extensive efforts were devoted to measure more nuclides of fragments.Experiments were carried out at HIMAC, NIRS. The synchrotron HIMAC provided high-energy C-12 ion beams, which bombarded a C-12 target. Emitted charged particles from reactions were detected with the gas-scintillation detector. Finally, we determined proton production double-differential cross sections at most forward angles zero to three degrees where measurements are very difficult in general. The energy range of measured protons was from 200 to 500 MeV.In addition, we carried out several measurements for detector test to allow energy calibrations. One was the measurements of crystal response to protons and other particles, which was made at JINR, Russia. The data show an important suggestion that the limit of the Birks treatment, and further analyses should be based on the Mayer-Murray universal curve approach. Further microscopic approach would be needed for deeper understanding.

粒子放射治疗是多种癌症最有效的治疗方法之一，因为它提供了治愈严重癌症并提高生活质量的可能性很高。为了有效抑制副作用，需要开发一种基于准确估计放射剂量的先进治疗计划的方法。核碎片在破坏DNA中起着关键作用，因此核数据是实现剂量估计系统的重要数据。由于测量这些具有非常高的线性能量传输的数据存在困难，因此有必要开发一种新的探测器系统。因此，我们开发了闪烁体探测器系统并将其应用于HIMAC、NIRS的核数据测量。人们付出了广泛的努力来测量更多的碎片核素。在HIMAC、NIRS 上进行了实验。同步加速器HIMAC提供高能C-12离子束，轰击C-12目标。用气体闪烁检测器检测反应中发射的带电粒子。最后，我们确定了大多数前向角为 0 到 3 度时的质子产生双微分横截面，一般来说，测量非常困难。测量的质子的能量范围为200至500 MeV。此外，我们对探测器测试进行了多次测量，以进行能量校准。其中之一是测量晶体对质子和其他粒子的响应，这是在俄罗斯 JINR 进行的。数据显示了 Birks 处理的局限性的重要建议，进一步的分析应基于 Mayer-Murray 通用曲线方法。需要进一步的微观方法才能更深入地理解。