Endovenous laser treatment with 1320nm Nd : YAG laser for primary varicose veins

1320nm Nd : YAG 激光静脉内激光治疗原发性静脉曲张

• 批准号: 17591324
• 负责人: SUGANO Norihide
• 金额: $ 2.26万
• 依托单位: Tokyo Medical and Dental University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2005
• 资助国家: 日本
• 起止时间: 2005 至 2007
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17591324/
• 关键词: Surgery; Varicose vein; Operation; Less invasive treatment; Laser; 静脈瘤

Objective: To clarify the efficacy and safety of a 1320 nm endovenous laser treatment (ELVT).Patients and Methods: Thirty-seven limbs in 32 patients with primary varicose veins were treated. Pulsed (50Hz) laser energy was applied at 5 Watts while the fiber was retracted at a speed of m/sec by the pull back system.Results: Although the initial success (occlusion) rate was 100% and the venous filling index was almost normal at 1 year after treatment, the clinical recurrence rate was 16.2% after a mean follow-up period of 633 days. The linear endovenous energy density (LEED) was significantly lower in the limbs with recurrence (45.5±5.6 vs. 52.3±12.3 J/cm, p<0.05). There was no major complication. Minor complications included 4 moderate bruising, 6 mild pains, and 1 saphenous nerve injury.Conclusion: 1320 nm EVLT was a safe and effective treatment, but a LEED of greater than 50 J/cm might be necessary to occlude the saphenous vein sufficiently.

目的：为了阐明1320 nm静脉腔内激光治疗（ELVT）的有效性和安全性，患者和方法：32例原发性静脉曲张患者的37条肢体接受了治疗。施加5 W脉冲（50 Hz）激光能量，同时拉回系统以m/s的速度回撤光纤。结果：尽管初始成功（闭塞）率为100%，治疗后1年静脉充盈指数几乎正常，但平均随访633天后临床复发率为16.2%。复发肢体的线性静脉能量密度（LEED）显著较低（45.5±5.6 vs. 52.3±12.3 J/cm，p<0.05）。无严重并发症。轻微并发症包括4例中度挫伤，6例轻度疼痛，1例隐神经损伤。结论：1320 nm EVLT是一种安全有效的治疗方法，但LEED大于50 J/cm可能是必要的，以充分闭塞隐静脉。

项目成果

Deep venous reconstructions:long-term outcome in patients with primary or postthrombotic deep venous insufficiency.

深静脉重建：原发性或血栓后深静脉功能不全患者的长期结果。

• 发表时间: 2007
• 期刊: Eur J Vasc Endocasc Surg 35(4)
• 作者: Lehtola A;Oinonen A;Sugano N;Alback A;Lepantalo M.
• 通讯作者: Lepantalo M.

Communicating Doppler-derived information in superficial venous surgery

在浅静脉手术中交流多普勒衍生信息

• 发表时间: 2007
• 期刊: Phlebology 22(3)
• 作者: Oinonen A.;Lehtola A.;Sugano N.;Alback A.;Lepantalo M.
• 通讯作者: Lepantalo M.

Effectiveness and combination of inferior vena cava filter for prevention against pulmonary embolism from deep vein thrombosis

下腔静脉滤器预防深静脉血栓肺栓塞的效果及组合

• 发表时间: 2007
• 作者: Fujita S;Sugano N;Inoue Y;Iwai T;Katada Y;Kishino M.
• 通讯作者: Kishino M.

Popliteal venous entrapment syndrome: a report of a case・

腘静脉卡压综合征1例报告・

• 发表时间: 2007
• 作者: Kudo T;Iwai T;Inoue Y;Sugano N. Jibiki M;Terasaki H.
• 通讯作者: Terasaki H.

【下肢静脈瘤をめぐる最近の諸問題】Laser・Ablation療法の現況.

[下肢静脉曲张的最新问题]激光/消融治疗的现状。

• 发表时间: 2007
• 期刊: 血管外科 26巻1号
• 作者: Oinonen A.;Lehtola A.;Sugano N.;Alback A.;Lepantalo M.;井上芳徳.;菅野範英.
• 通讯作者: 菅野範英.