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Synthesis of thermosensitive double-layer gel by polymer reaction

聚合物反应合成热敏双层凝胶

基本信息

批准号：
18550195
负责人：
IIZAWA Takashi
金额：
$ 2.6万
依托单位：
Hiroshima University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
2006
资助国家：
日本
起止时间：
2006 至 2007
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-18550195/
关键词：
Thermosenseitive Gel Polymer Reaction Double-layer Gel Bending Behavior Core-shell Type Gel 屈曲性

项目摘要

The purpose of this study is to establish synthetic method of asymmetric, thermosensitive double-layer gel by amidation of poly(acrylic acid) gel-1,8-diazabicyclo-[5,4,0]-7-undecene salt (DAA) with alkylamine.1. The first amidation of DAA with alkylamines proceeded nearly quantitatively at 80℃ in the presence of triphenylphosphite to give the corresponding DAA-poly(N-alkylacrylamide) (PNAA) core-shell type gels. The thickness of the shell layer was controlled by the reaction time. PNAA(2)-PNAA(1) core-shell type gels were prepared by the second amidation of the DAA-PNAA core-shell type gel with another alkylamine under the similar conditions as the first amidation.2. The swelling/de-swelling of shell layers and cores in the PNAA(2)-PNAA(1) core-shell type gels occurred almost independently in response to the temperature changes.3. The semi-cylindrical, double-layer gels were prepared by cutting the cylindrical PNAA(2)-PNAA(1) core-shell type gels into halves.4. The resulting semi-cylindrical, double-layer gels were markedly bent in water at temperatures between the lower critical solution temperatures (LCSTs) of PNAA(2) and PNAA(1). The reversible bending behavior was observed in response to stepwise temperature changes cross the LCSTs. However, the destruction on the boundary occurred gradually, since the shape of the bent gel was extremely distorted.5. A new approach to the preparation of asymmetric thermosensitive PNAA(2)-PNAA(1) double-layer gels, which were not damaged by this deformation, by several procedures was proposed.6. A thin long, asymmetric, thermosensitive double-layer gel was prepared. This gel can be bent in zigzag with high-speed response.

本研究的目的是通过聚丙烯酸凝胶-1，8-二氮杂双环[5，4，0]-7-十一烯盐（DAA）与烷基胺的酰胺化反应，建立不对称温敏双层凝胶的合成方法.在亚磷酸三苯酯存在下，DAA与烷基胺在80℃下进行了几乎定量的第一次酰胺化反应，得到了相应的DAA-聚（N-烷基丙烯酰胺）（PNAA）核壳型凝胶。壳层的厚度由反应时间控制。在与第一次酰胺化类似的条件下，通过DAA-PNAA核壳型凝胶与另一种烷基胺的第二次酰胺化制备PNAA（2）-PNAA（1）核壳型凝胶。PNAA（2）-PNAA（1）核壳型凝胶中壳层和核的溶胀/去溶胀几乎独立地响应于温度变化而发生.通过将圆柱形PNAA（2）-PNAA（1）核-壳型凝胶切成两半来制备半圆柱形双层凝胶.所得半圆柱形双层凝胶在PNAA（2）和PNAA（1）的低临界溶解温度（LCST）之间的温度下在水中显著弯曲。观察到可逆弯曲行为响应于跨越LCST的逐步温度变化。然而，由于弯曲凝胶的形状极度扭曲，边界上的破坏逐渐发生.提出了一种新的制备不受这种变形破坏的不对称温敏PNAA（2）-PNAA（1）双层凝胶的方法.制备了一种薄长、不对称的温敏双层凝胶。该凝胶可以高速响应地弯曲成锯齿形。