Study on production domestic animals biosynthesized conjugated fatty acids that carries anti-obesity effects

据报道，共轭亚油酸对癌症和肥胖症有效。本研究将共轭亚油酸异构酶基因(PAISOM)导入牛细胞。获得了稳定表达PAISOM基因的细胞。我们还成功地从PAISOM-细胞中获得了克隆胚胎。然而，PAISOM细胞中的脂肪酸的气相色谱没有表明是共轭亚油酸，但我们检测到一个未知的峰，但很可能是由共轭亚油酸延伸而来的共轭花生四烯酸。

Conjugated linoleic acid has been reported to be effective for cancers and obesity. In this study, a gene for an isomerase for conjugated linoleic acid (PAISOM) was introduced into bovine cells. We obtained cells stably transfected with PAISOM gene. We also successfully produced cloned embryos from the PAISOM-cells. However, Gas chromatography of fatty acids in the PAISOM-cells did not indicate the conjugated linoleic acid, but we detected a peak unknown but likely to be conjugated arachidonic acid that were elongated from conjugated linoleic acid.