Chemical state analysis of rarely contained biological metallic element using X-ray absorption fine structure (XAFS) analysis

使用 X 射线吸收精细结构 (XAFS) 分析对很少含有的生物金属元素进行化学状态分析

• 批准号: 18390509
• 负责人: UO Motohiro
• 金额: $ 11.78万
• 依托单位: Hokkaido University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2006
• 资助国家: 日本
• 起止时间: 2006 至 2009
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-18390509/
• 关键词: XAFS; X線吸収微細構造; 微小部分析; 生体材料; 歯科材料; 金属; 化学状態; チタン; 溶出; 歯科用材料; 歯科理工学; インプラント; ニッケルチタン合金

In this study, the chemical state of metallic elements and micro foreign bodies contained in the biological tissues were analyzed using XAFS method and the behavior of dental and medical alloys (e.g.titanium, nickel-titanium alloy, chromium-based alloy) was evaluated. Titanium in the surrounding tissues of dental and medical implants was usually existed as the metallic Ti, but, the titanium oxide was also detected. The titanium oxide was considered as derived from the dissolved and precipitated Ti. Nickel was existed as the ionic state in the surroundings of nickel-based alloy, then, the toxic effect of Ni ion to the surrounding tissues was concerned. In addition, trace element in the tussues (e.g.Se) analysis and micro XAFS analysis were also carried. In conclusion, the possibility of XAFS analysis for the biological tissue was suggested.

在这项研究中，使用XAFS方法分析了生物组织中包含的金属元素和微小异物的化学状态，并对牙科和医用合金（如钛、镍钛合金、铬基合金）的行为进行了评价。钛在牙科和医用植入物周围组织中通常以金属钛的形式存在，但也可检出氧化钛。认为氧化钛来源于溶解和沉淀的Ti。镍以离子状态存在于镍基合金的周围环境中，因此，镍离子对周围组织的毒性作用受到关注。此外，还对样品中的微量元素（如硒）进行了分析，并对样品进行了XAFS分析。最后，提出了XAFS分析生物组织的可能性。

项目成果

Preparation and Properties of Dental Composite Resin Cured under Near Infrared Irradiation

• DOI: 10.2494/photopolymer.22.551
• 发表时间: 2009-01-01
• 期刊: JOURNAL OF PHOTOPOLYMER SCIENCE AND TECHNOLOGY
• 影响因子: 0.8
• 作者: Uo, Motohiro;Kudo, Eiki;Kogo, Yasuo
• 通讯作者: Kogo, Yasuo

Micro XAFS analysis of metallic element containing biological specimens using the polycapillary focusing X-ray optics

使用多毛细管聚焦 X 射线光学器件对含有金属元素的生物样本进行显微 XAFS 分析

• 发表时间: 2009
• 作者: Uo M.;Asakura K.
• 通讯作者: Asakura K.

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Effect of surface condition of dental zirconia ceramic (Denzir) on bonding

• DOI: 10.4012/dmj.25.626
• 发表时间: 2006-09-01
• 期刊: DENTAL MATERIALS JOURNAL
• 影响因子: 2.5
• 作者: Uo, Motohiro;Sjogren, Goran;Bergman, Maud
• 通讯作者: Bergman, Maud

XAFS Analysis of Ti and Ni Dissolution from Pure Ti, Ni-Ti Alloy, and SUS304 in Soft Tissues

• DOI: 10.1246/cl.2008.958
• 发表时间: 2008-09-05
• 期刊: CHEMISTRY LETTERS
• 影响因子: 1.6
• 作者: Uo, Motohiro;Asakura, Kiyotaka;Watari, Fumio
• 通讯作者: Watari, Fumio