Post longitudinal extension of spinal cord injury in spinal and section and contusion

本研究评价了脊髓损伤后纵向延伸在脊髓节段和挫伤后的变化。6只狗用于急性期的实验，分为脊髓节段和脊髓挫伤两组。检测脊髓损伤后即刻脊髓诱发电位(SCEP)和运动诱发电位(MEP)。在脊髓节段，SCEP波幅在脊髓节段后即刻降低2 cm。在脊髓挫伤后，脊髓挫伤后即刻SCEP波幅降低2 cm。6只犬用于慢性期实验，分为脊髓挫伤组、节段性脊髓挫伤组和脊髓挫伤组。在脊髓损伤后1周进行SCEP和MEP检测。在脊髓节段，脊髓损伤后1周，脊髓诱发电位波幅下降3.5≠±0.3 cm。脊髓挫伤组脊髓挫伤后1周，SCEP波幅较伤前降低25±0.5 cm，术后1周取材进行组织学和光镜观察。脊髓切片上2~4 cm处可见白质和灰质损伤。在脊髓挫伤中，病理上发现了一种“牙膏现象”。这是一种当脊髓实质组织被挤压并穿透受压水平以上和之下时发生的现象。脊髓挫伤上方2~4 cm处可见灰质损害。我们认为，脊髓节段压迫脊髓类似脊髓挫伤，由于在结扎脊髓时会出现这种牙膏现象，因此最好用手术刀处理，而不是结扎，以避免损伤脊髓。本研究提示继发性脊髓损伤发生在脊髓损伤后数天。

The present study evaluated post longitudinal extension of spinal cord injury in spinal cord section and contusion.Six dogs were used for the experiments of the acute phase and divided into two groups ; spinal cord section and spinal cord contusion. Spinal cord evoked potentials (SCEP) and Motor evoked potentials (MEP) were measured immediately after spinal cord oration and contusion. In the spinal cord section, the amplitudes of the SCEP decreased 2cm above section immediately after spinal cord section. In the spinal cord contusion, the amplitudes of the SCEP decreased 2 cm above contusion immediately attar spinal cord contusion.Six dogs were used for the experiments of the chronic phase and divided into two groups ; spinal and section and spinal cord contusion. SCEP and MEP were measured one week after spinal cord section and contusion. In the spinal cord section, the amplitudes of the SCEP decreased 3.5≠±0.3 cm above section one week after spinal cord oration. In the spinal cord contusion, the amplitudes of the SCEP decreased 25±0.5cm above contusion one week after spinal cord contusion.Histology and microscopy of the dogs one week after spinal cord section and contusion were evaluated. In the spinal cord section, white and gray matter damage was seen 2-4 cm above spinal cord section. In the spinal cord contusion, a "tooth paste phenomenon" was recognized pathologically. This is a phenomenon that occurs when parenchymal tissue of spinal cord is squeezed and penetrates above and below the level of compression. Gray matter damage was seen 2-4 cm above spinal cord contusion. We considered that spinal cord section compressed spinal cord like spinal contusionBecause such a tooth paste phenomenon occurs when a spinal cord is ligated, transaction with a scalpel, instead of ligation, is desirable to avoid damaging spinal cord. The present study suggests that secondary spinal cord injury occurs several days after spinal cord injury.