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Physiological analysis of pelvic and epidural plexus veins in rabbits

家兔盆腔和硬膜外丛静脉的生理分析

基本信息

批准号：
09671478
负责人：
TOMITA Katsuro
金额：
$ 1.41万
依托单位：
Kanazawa University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
1997
资助国家：
日本
起止时间：
1997 至 1998
项目状态：
已结题

项目摘要

Excessive bleeding is a significant problem during total sacrectomy. Ligation of the internal iliac veins to control bleeding from the pelvic venous plexus has been reported to be mandatory. However, despite ligation of the internal iliac veins, excessive hemorrhage from the pelvic and epidural venous plexuses is often encountered. We postulated that ligation of the internal iliac veins increases blood loss during total sacrectomy and we investigated the influence of ligation of the internal iliac veins on the pelvic and epidural venous plexuses in white rabbits. We also investigated the influence of the animal's operative position on the epidural venous pressure. Venography was performed to study the differences in blood flow patterns before and after ligation of the internal iliac veins. Without ligation, contrast medium passed into the inferior vena cava, but not into the epidural venous plexus. The epidural venous plexus was contrast-filled when the internal iliac veins were ligated. The pressure in the internal iliac veins was increased with their ligation, and decreased with ligation of the abdominal aorta. The pressure was also decreased with intentional bleeding from the epidural venous plexus, and with changing the animal's position to headdown. Ligation of the internal iliac veins leads to congestion of the pelvic venous and epidural venous plexuses. Ligation of the internal iliac arteries and positioning the animal headdown were effective ways to resolve the congestion in these venous plexuses.

大出血是全骶骨切除术中的一个重要问题。据报道，结扎髂内静脉以控制盆腔静脉丛出血是强制性的。然而，尽管结扎髂内静脉，盆腔和硬膜外静脉丛的过度出血仍是经常遇到的。我们假设髂内静脉结扎会增加全骶骨切除术中的失血量，并研究了髂内静脉结扎对白色家兔盆腔和硬膜外静脉丛的影响。我们还研究了动物的手术体位对硬膜外静脉压的影响。通过静脉造影观察髂内静脉结扎前后血流模式的变化。在不结扎的情况下，造影剂进入下腔静脉，但不进入硬膜外静脉丛。髂内静脉结扎时，硬膜外静脉丛被造影剂填充。髂内静脉的压力随着髂内静脉的结扎而增加，随着腹主动脉的结扎而降低。硬膜外静脉丛故意出血，并改变动物的位置，头向下的压力也降低。髂内静脉结扎导致盆腔静脉和硬膜外静脉丛充血。结扎髂内动脉和将动物头朝下定位是解决这些静脉丛充血的有效方法。