Relationship between sperm fertilizing ability and intracellular signal transduction.

与正常精子相比，具有异常形态的精子的基线和峰值荧光较低。不育夫妇形态正常精子卵泡液诱导的[Ca^<2+>]i升高低于健康供体形态正常精子。本研究表明，正常人精子中形态异常的精子存在信号转导障碍，不育患者精子中形态正常的精子与正常人精子相比存在信号转导障碍。

The baseline and peak fluorescence of the spermatozoa with abnormal morphology was lower when compared with normal spermatozoa. Follicular fluid-induced [Ca^<2+>]i increase of morphologically normal spermatozoa from infertile couples was lower than that of morphologically normal spermatozoa from healthy donors. This study shows that spermatozoa with abnormal morphology have disorders of signal transduction in healthy donors, and normal shaped sperm from infertile patients have disorders of signal transduction comparing that from healthy donors.