Development of new adhesive systems based on the characteristics of primary tooth dentin

根据乳牙牙本质特性开发新型粘接体系

基本信息

批准号：
18592240
负责人：
HOSOYA Yumiko
金额：
$ 2.43万
依托单位：
Nagasaki University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
2006
资助国家：
日本
起止时间：
2006 至 2007
项目状态：
已结题

项目摘要

Primary dentin has significantly lower physical properties than permanent tooth dentin, and more susceptible to chemicals. The purpose of this study was to develop a new adhesive system with mild acid-etching ability, adequate penetration into the caries-affected dentin and simple and easy to clinical use.Materials, Methods and Results :Sun-Medicals 4-META one-step self-etch adhesives AQ Bond Plus (AQBP)or Hybrid Bond (HB, new product)was applied on the sound or caries-affected primary tooth dentin.#Test 1 : resin-dentin interfaces were measured with a nano-indentation tester and the hardness (H)and Young's modulus(Y)were calculated.#Test 2 : Ultrastructures of resin-dentin interfaces were observed with FE-SEM, SEM and TEM.(1)Only in the carious-HB group, the H and Y of the interfacial dentin were not significantly lower than those obtained from 10-70 μm beneath the interface.(2)Both in the sound-AQBP and sound-HB groups, the H of the interfacial dentin was significantly lower than those obtained from 10-70 μm beneath the interface.(3)Compared with sound primary tooth dentin, the H and Y values of adhesive layer of AQBP and HB were about 1/2 and 1/3, respectively.(4)The hybrid layer of both adhesives was about 1 μm thick.(5)In the sound dentin, silver nanoleakage was observed along the interface both in the AQBP and HB groups.(6)In the carious teeth, silver nanoleakage was not seen in the hybrid layer and many of the dentinal tubules were filled with mineral deposits that prevented silver nanoleakage. However, silver deposits were seen in the underlying porous caries-affected dentin.In both adhesive groups, silver nanoleakage was observed in these resin-dentin interfaces and porous caries-affected dentin. Those results might deteriorate effect of clinical prognosis of resin restorations. Further improvements of one-step self-etch adhesives are required to obtain stable adhesion

原发性牙本质的物理特性明显低于永久性牙齿牙本质，并且更容易受到化学物质的影响。 The purpose of this study was to develop a new adhesive system with mild acid-etching ability, adequate penetration into the carries-affected dentin and simple and easy to clinical use.Materials, Methods and Results :Sun-Medicals 4-META one-step self-etch adhesives AQ Bond Plus (AQBP) or Hybrid Bond (HB, new product)was applied on the sound or carries-affected primary tooth dentin.#Test 1:通过纳米注册测试仪和硬度（H）和Young的模量（Y）测量树脂丁丁素的界面。（2）在声音AQBP和声音HB组中，界面牙本质的H明显低于从界面下方10-70μm获得的界面。（3）与声音原发性牙齿牙本质相比，AQBP和HB的粘附层的H和Y值分别为1/2和1/3和1/3）。厚。（5）在声音牙本质中，沿AQBP和HB组的界面都观察到银色的nanoLeakage。（6）在龋齿的牙齿中，在混合层中看不到银nanoleakage，许多牙齿管中都充满了矿物质沉积物，这些沉积物充满了防止银色nanoleakage的矿物质。然而，在受龋齿影响的牙本质中看到了银沉积物。在两个粘合剂基团中，在这些树脂丁丁界面中都观察到银纳米船，并在受多的龋齿影响的牙本质中观察到。这些结果可能对树脂修复的临床预后侦探作用。需要进一步改进一步自蚀刻粘合剂才能获得稳定的粘合剂