Analysis of syntaxin 1 gene knockout mice as an animal model for autistic disorder
Analysis of syntaxin 1 gene knockout mice as an animal model for autistic disorder
批准号:
19300133
负责人:
AKAGAWA Kimio
金额:
$9.15万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2009
中文摘要
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英文摘要
It was suggested by studying syntaxin1A (sy1A) or syntaxin1B (sy1B) gene knockout mice that sy1A and sy1B function in monoaminergic and mainly in glutamatergic fast transmission respectively. These findings overturned the usual thought that sy1a and sy1B played similar roles in synaptic function.
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Syntaxin 8 has two functioiially distinct di-leucine-based motifs.
突触融合蛋白 8 具有两个功能不同的基于二亮氨酸的基序。
DOI:
--
发表时间:
2007
期刊:
Cellular and Molecular Biology Letters 13
影响因子:
--
作者:
[Kozai, T., et. al., K.Kasai]
通讯作者:
K.Kasai
The syntaxin 5 isoforms Syx5 and Syx5L have distinct effects on the processing of s-amyloid precursor protein.
突触融合蛋白 5 亚型 Syx5 和 Syx5L 对 s-淀粉样前体蛋白的加工具有明显的影响。
DOI:
--
发表时间:
2009
期刊:
J. Biochem Vol.146
影响因子:
--
作者:
[K. Suga, A. Saito, T. Tomiyama, H. Mori, K. Akagawa]
通讯作者:
K. Akagawa
DOI:
10.1111/j.1460-9568.2010.07269.x
发表时间:
2010-07-01
期刊:
EUROPEAN JOURNAL OF NEUROSCIENCE
影响因子:
3.4
作者:
[Fujiwara, Tomonori, Snada, Masumi, Akagawa, Kimio]
通讯作者:
Akagawa, Kimio
Enhancement of sunaptic transmission and nociceptive behavior inHPC-1/syntaxin 1A knockout mice following perinheral nerve injury.
HPC-1/syntaxin 1A 敲除小鼠周围神经损伤后光触传递和伤害行为的增强。
DOI:
--
发表时间:
2007
期刊:
European Journal. of Neuroscience 26
影响因子:
--
作者:
[Miyasaka, N., Morimoto, K., Tsubokawa, T., Higashijima, S., Okamoto, H., Yoshihara, Y., T.Takasuki]
通讯作者:
T.Takasuki
Imaging analysis reveals mechianistic differences between first and second phase insulin exocytosis
成像分析揭示第一相和第二相胰岛素胞吐作用之间的机制差异
DOI:
--
发表时间:
2007
期刊:
Journal of Cell Biology 177
影响因子:
--
作者:
[Hosokawa K, Nishi M, Sakamoto H, Tanaka Y, Kawata M, M.Ohara-Imaizumi]
通讯作者:
M.Ohara-Imaizumi
共 13 条
STUDY OF A NEURON-SPECIFIC PROTEIN,HPC-1, WHICH REGULATES NEURONAL SPROUTING.
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批准号:07458214
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$4.48万
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财政年份:1995
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负责人:AKAGAWA Kimio
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依托单位:
Studies of Neuronal Properties in the Reaggregate Cultures of Rat Retinane
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批准号:63570064
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.34万
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财政年份:1988
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负责人:AKAGAWA Kimio
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依托单位:
海外基金