Uterodomes and the evolution of viviparity

子宫穹窿和胎生的进化

• 批准号: DP0343428
• 负责人: Em/Prof Michael Thompson
• 金额: $ 23.04万
• 依托单位: The University of Sydney
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2003
• 资助国家: 澳大利亚
• 起止时间: 2003-01-01 至 2005-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0343428
• 关键词: Uterodomes; evolution; viviparity

We will test the hypothesis that uterodomes, which are cell structures unique to the early pregnant uterus in mammals, and the cellular changes accompanying their development, are essential to the evolution of viviparity in amniotes. The proposal stems from our recent discovery that uterodomes develop in the uteri of viviparous lizards as well as in mammals, suggesting key commonalities at the cellular level in the evolution of live birth across amniote vertebrates. We will take advantage of the unique combination of placental types among Australian lizards, including a species with both oviparous and viviparous populations.

我们将测试的假设，子宫，这是独特的细胞结构，在哺乳动物的早期妊娠子宫，和细胞的变化，伴随着他们的发展，是必不可少的胎生的进化在哺乳动物。这一提议源于我们最近的发现，即胎生蜥蜴和哺乳动物的子宫中都有子宫体发育，这表明在胎生脊椎动物活产进化过程中，细胞水平上存在关键的共性。我们将利用澳大利亚蜥蜴中胎盘类型的独特组合，包括一个既有卵生又有胎生种群的物种。