Evaluation of effects of salt reduction on blood pressure and behavior with genetic polymorphism information

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We evaluated the effects of our salt reduction intervention developed by the behavioral theory on blood pressure and behavior with genetic polymorphism information. We assessed the interaction of salt intake and genetic polymorphisms selected by candidate gene approach and Genome Wide Association Studies in Japanese population. Risk allele score of our results showed significant linear association with blood pressure. Information of polymorphism which affects blood pressure and the responsiveness to the salt reduction was gained which will be useful for future tailor-made prevention of hypertension.