Analysis of the relationship between epigenetic disorder, micro RNA in gastroenterological cancer
Analysis of the relationship between epigenetic disorder, micro RNA in gastroenterological cancer
批准号:
19390195
负责人:
YOKOSUKA Osamu
金额:
$12.06万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2008
中文摘要
点击翻译按钮获取中文摘要
英文摘要
脱メチル化剤を培養細胞に投与し、発現が回復するマイクロRNAをエピジェネティックな因子による発現制御を受けるマイクロRNA候補とし、解析を行った.対象とした培養細胞は、食道癌由来、肝細胞癌由来、大腸癌由来の培養細胞.hsa-mir-26b,517a, 372, 373, 519, 520gに注目し、細胞増殖能を変化させることを明らかにした.一部のマイクロRNAにおいて、プロモーター領域の異常メチル化を明らかにし、異常メチル化により発現が制御され、癌細胞の増殖に関与することが明らかになった.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
登录
查看更多内容
DOI:
10.3892/or_00000022
发表时间:
2008-08-01
期刊:
ONCOLOGY REPORTS
影响因子:
4.2
作者:
[Arai, Makoto, Imazeki, Fumio, Yokosuka, Osamu]
通讯作者:
Yokosuka, Osamu
genes up-regulated by the demethylating agent, 5-aza- 2' deoxycytidine, in esophageal squamous cell carcinoma
食管鳞状细胞癌中去甲基化剂 5-aza-2 脱氧胞苷上调的基因
DOI:
--
发表时间:
2008
期刊:
Oncol Rep 20(2)
影响因子:
--
作者:
[新井誠人、今関文夫、横須賀收, 他6名]
通讯作者:
他6名
Quantitative analysis of vascular endothelial growth factor in liver metastases from pancreatic carcinoma as a predictor of chemotherapeutic effect and prognosis
胰腺癌肝转移中血管内皮生长因子的定量分析作为化疗效果和预后的预测因子
DOI:
--
发表时间:
2008
期刊:
Clin Cancer Res. 14(22)
影响因子:
--
作者:
[Hiramatsu R, Hara T, Akimoto H, Takikawa O, Kawabe T, Isobe K, Nagase F, 太和田勝之]
通讯作者:
太和田勝之
Quantitative analysis of vascular endothelial growth factor in liver metastases from pancreatic carcinoma as a predictor of chemotherapeutic effect, prognosis
胰腺癌肝转移中血管内皮生长因子的定量分析作为化疗效果和预后的预测因子
DOI:
--
发表时间:
2008
期刊:
Clin Cancer Res 14(22)
影响因子:
--
作者:
[太和田勝之、横須賀收, 他5名]
通讯作者:
他5名
Analysis of the complete hepatitis B virus genome in patients with gellotype C chronic hepatitis and hep.atocellular carcinoma
丙型慢性肝炎及肝癌患者乙型肝炎病毒全基因组分析
DOI:
--
发表时间:
2007
期刊:
Cancer Science 98
影响因子:
--
作者:
[Yurimoto S, Masaki T, 6 others (6)nd, 張 凱宇]
通讯作者:
張 凱宇
共 10 条
The analysis of the predictive marker for the efficacy of the angiogenesis inhibitor for the treatment of hepatocellular carcinoma
-
批准号:21390225
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$11.23万
-
财政年份:2009
-
负责人:YOKOSUKA Osamu
-
依托单位:
Analysis of Viral and host factors influencing the pathophysiology and effect of therapy of pesisitent hepatitis virus infection
-
批准号:16590576
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.24万
-
财政年份:2004
-
负责人:YOKOSUKA Osamu
-
依托单位:
STUDIES ON HOST FACTORS RELATED TO FULMINANT HEPATITIS
-
批准号:14570444
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.24万
-
财政年份:2002
-
负责人:YOKOSUKA Osamu
-
依托单位:
FUNCTIONAL ROBES OF HEPATITIS A VIRUS NONSTRUCTURAL PROTEINS IN SIGNAL TRANSDUCTION
-
批准号:12670458
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.98万
-
财政年份:2000
-
负责人:YOKOSUKA Osamu
-
依托单位:
HBV DNA integration and expression of HBx messages in HCC
-
批准号:10670451
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.43万
-
财政年份:1998
-
负责人:YOKOSUKA Osamu
-
依托单位:
ANALYSES OF HEPATITIS A VIRUS GENOME FROM PATIENTS WITH FULMINANT TYPE A HEPATITIS
-
批准号:08457162
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$3.9万
-
财政年份:1996
-
负责人:YOKOSUKA Osamu
-
依托单位:
ANALYSIS OF MUTATIONS IN HEPATITIS B VIRUS ENHANCER 2/CORE PROMOTER ANT THEIR FUNCTIONAL ROLES IN HEPATITIS B
-
批准号:06670521
-
项目类别:Grant-in-Aid for General Scientific Research (C)
-
资助金额:$1.34万
-
财政年份:1994
-
负责人:YOKOSUKA Osamu
-
依托单位:
EXPRESSION OF HEPATITIS C VIRUS ENVELOPE RELATED PROTEINS AND DETECTION OF ANTIBODIES TO PROTEINS.
-
批准号:04670408
-
项目类别:Grant-in-Aid for General Scientific Research (C)
-
资助金额:$1.34万
-
财政年份:1992
-
负责人:YOKOSUKA Osamu
-
依托单位:
Detection of hepatitis C virus RNA by sensitive PCR method
-
批准号:02807072
-
项目类别:Grant-in-Aid for General Scientific Research (C)
-
资助金额:$1.02万
-
财政年份:1990
-
负责人:YOKOSUKA Osamu
-
依托单位:
Detection of hepatitis B virus nucleic acid by PCR method.
-
批准号:63570310
-
项目类别:Grant-in-Aid for General Scientific Research (C)
-
资助金额:$1.54万
-
财政年份:1988
-
负责人:YOKOSUKA Osamu
-
依托单位:
海外基金