Molecular epidemiological survey on Babesia parasites in Asia and Africa

亚洲和非洲巴贝虫寄生虫分子流行病学调查

• 批准号: 19405044
• 负责人: IGARASHI Ikuo
• 金额: $ 10.73万
• 依托单位: Obihiro University of Agriculture and Veterinary Medicine
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2007
• 资助国家: 日本
• 起止时间: 2007 至 2010
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19405044/
• 关键词: バベシア病; アジア; アフリカ; 診断; 疫学調査; 遺伝子解析

Babesiosis causes great economic losses to animal industry worldwide and designated as an exotic infectious disease. Objective of the present study was to develop new serological and molecular diagnostic tests against babesiaosis to do molecular epidemiological survey on babesiosis in Asia and Africa, and to contribute for strength of the quarantine system in Japan. As a result, new serological and molecular diagnostics were developed against bovine and equine babesiosis. The epidemiological surveillance in four countries in Asia Africa demonstrated high prevalence of babesiosis in these regions.

巴贝斯虫病在世界范围内给畜牧业造成了巨大的经济损失，被列为外来传染病。本研究的目的是建立新的巴贝斯虫病血清学和分子诊断试验，以便在亚洲和非洲进行巴贝斯虫病的分子流行病学调查，并为加强日本的检疫制度做出贡献。因此，针对牛和马巴贝斯虫病的血清学和分子诊断技术应运而生。在亚非四个国家进行的流行病学监测表明，这些地区巴贝斯虫病的流行率很高。

项目成果

Evaluation of Babesia bigemina 200kDa recombinant antigen in enzyme-linked immunosorbent assay

酶联免疫吸附法评价二联巴贝虫 200kDa 重组抗原

• 发表时间: 2009
• 期刊: Parasitol.Res. 105
• 作者: Altangerel K;Alhassan A;Iseki H;Sivakumar T;Boldbaatar D;Yokoyama N;Igarashi I
• 通讯作者: Igarashi I

Application of the immunochromatographic test (ICT) for the diagnosis of tick borne-disease

免疫层析检测（ICT）在蜱传疾病诊断中的应用

• 发表时间: 2008
• 作者: 五十嵐郁男;ほか7名
• 通讯作者: ほか7名

Comparative evaluation of the sensitivity of LAMP, PCR and in vitro culture methods for the diagnosis of equine piroplasmosis

• DOI: 10.1007/s00436-006-0430-6
• 发表时间: 2007-04-01
• 期刊: PARASITOLOGY RESEARCH
• 影响因子: 2
• 作者: Alhassan, Andy;Govind, Yadav;Igarashi, Ikuo
• 通讯作者: Igarashi, Ikuo

Development of Taqman-Based Real-Time PCR Assaya for Diagnostic Detection of Babesi

基于 Taqman 的实时 PCR 检测巴贝西诊断检测的开发

• 发表时间: 2007
• 期刊: Am J Trop Med Hyg. 77:837-841. 77
• 作者: Kim C;Iseki H;Herbas MS;Yokoyan
• 通讯作者: Yokoyan

Comparison of polymerase chain reaction methods for the detection of Theileria equi infection using whole blood compared with pre-extracted DNA samples as PCR templates

• DOI: 10.1007/s11250-007-9025-1
• 发表时间: 2007-06-01
• 期刊: TROPICAL ANIMAL HEALTH AND PRODUCTION
• 影响因子: 1.7
• 作者: Alhassan, A.;Iseki, H.;Igarashi, I.
• 通讯作者: Igarashi, I.