Basic study that examining immune regulatory effect of soy isoflavones.

大豆食品在亚洲国家已经食用了几个世纪。人类临床和流行病学研究已经揭示了摄入豆制品的许多潜在益处。因此，在本研究中，我们研究了雌马酚对BALB/c小鼠卵白蛋白（OVA）特异性T细胞和B细胞反应的影响。用20mg/kg雌马酚处理的小鼠，其ova特异性IgE水平明显高于对照组。此外，雌马酚在BALB/c小鼠中引起dss诱导的结肠炎。

Soy foods have been consumed for centuries in Asian countries. Human clinical and epidemiological studies have revealed many potential benefits of intake of soy products. In this study, we therefore investigated the effects of equol on ovalbumin (OVA)-speficic T cell and B cell responses in BALB/c mice. Mice that had been treated with 20mg/kg equol showed a significantly higher level of OVA-specifc IgE than that in control mice. Furthermore, equol perpetrated DSS-induced colitis in BALB/c mice.