Developmental mechanism of ionocytes in the skin of zebfaish larvae to acclimate fresh water

zebfaish幼虫皮肤离子细胞适应淡水的发育机制

• 批准号: 19570201
• 负责人: HOSHIJIMA Kazuyuki
• 金额: $ 3万
• 依托单位: Tokyo Institute of Technology
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2007
• 资助国家: 日本
• 起止时间: 2007 至 2009
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19570201/
• 关键词: 環境; 発現制御; 発生・分化; イオンホメオスタシス; ホメオスタシス; zinc-finger nuclease; マイクロアレイ

淡水魚の体表に発達する表層イオン代謝細胞は,淡水中より様々なイオンを取り込み,体内のイオン濃度を一定に保つために必要不可欠な細胞群と考えられてきた。我々はこれまでにfoxi3a遺伝子が表層イオン代謝細胞の発生分化に必須であることを明らかにしてきたが,本研究ではさらにfoxi1遺伝子,deltaC遺伝子,およびgcm2遺伝子がその細胞分化形成に関わっていることを示し,それら遺伝子間相互作用,作用機序を明らかにした。

In fresh water, the surface of the body is up to the surface, and the cells are on the surface of the body. In fresh water, the temperature in the body must be protected. It is necessary to test the cell population. In this study, the cells of foxi1, deltaC, and gcm2 were differentiated to form a sign of cell differentiation, and the interaction between them was clearly explained in this study.

项目成果

Localization of ammonia transporter Rhcgl in mitochondrion-rich cells of yolk sac, gill, and kidney of zebrafish and its ionic strength-dependent expression.

氨转运蛋白 Rhcgl 在斑马鱼卵黄囊、鳃和肾脏富含线粒体的细胞中的定位及其离子强度依赖性表达。

• 发表时间: 2007
• 期刊: Am. J. Physiol. Regul. Integr. Comp. Physiol. 293
• 作者: T. Nakada;K. Hoshijima;M. Esaki;S. Nagayoshi;K. Kawakami;and S. Hirose
• 通讯作者: and S. Hirose

Mechanism of development of ionocytes rich in vacuolar-type H+-ATPase in the skin of zebrafish larvae

• DOI: 10.1016/j.ydbio.2009.02.026
• 发表时间: 2009-05-01
• 期刊: DEVELOPMENTAL BIOLOGY
• 影响因子: 2.7
• 作者: Esaki, Masahiro;Hoshijima, Kazuyuki;Hirose, Shigehisa
• 通讯作者: Hirose, Shigehisa

Localization of ammonia transporter Rhcg 1 in mitochondrion-rich cells of yolk sac, gill, and kidney of zebrafish and its ionic strength-dependent expression

• DOI: 10.1152/ajpregu.00248.2007
• 发表时间: 2007-10-01
• 期刊: AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
• 影响因子: 2.8
• 作者: Nakada, Tsutonm;Hoshijima, Kazuyuki;Hirose, Shigehisa
• 通讯作者: Hirose, Shigehisa

Expression of endocrine genes in zebrafish larvae in response to environmental salinity

• DOI: 10.1677/joe-07-0003
• 发表时间: 2007-06-01
• 期刊: JOURNAL OF ENDOCRINOLOGY
• 影响因子: 4
• 作者: Hoshijima, Kazuyuki;Hirose, Shigehisa
• 通讯作者: Hirose, Shigehisa

Chromosomal Position Mediates Spinal Cord Expression of a dbx1a Enhancer

• DOI: 10.1002/dvdy.22122
• 发表时间: 2009-11-01
• 期刊: DEVELOPMENTAL DYNAMICS
• 影响因子: 2.5
• 作者: Gribble, Suzanna L.;Nikolaus, O. Brant;Dorsky, Richard I.
• 通讯作者: Dorsky, Richard I.