Bioorganic Research on Biologically Active Natural Products towards Development of Agrochemical and Medicinal Lead Compounds

对具有生物活性的天然产物进行了生物有机研究。全合成：多刺菌素抗生素类似物、植物毒素T-β-L和pyricuols、海洋拒食剂蝶烯酮、植物激素茉莉酸和gizzerosine。局部合成：抗生素帕霉素，螺芬菌素和enacyloxins，抗血管生成皮质抑素。烯酰氧菌素、紫杉烷、柠檬苦素类和棘品的分离和结构鉴定。

Bioorganic research on biologically active natural products have been achieved. Total synthesis : analogs of polynactin antibiotics, phytotoxin T-beta-L and pyricuols, marine antifeedant pteroenone, plant hormone jasmonic acids, and gizzerosine. Patial synthesis : antibiotics pamamycis, spirofungins and enacyloxins, and anti-angiogenetic cortistatins. Isolation and structure elucidation : enacyloxins, taxanes, limonoids and echinopines.