Investigation on the mechanism underlying antipyretic effect of atrial natriuretic peptide within the brain
Investigation on the mechanism underlying antipyretic effect of atrial natriuretic peptide within the brain
批准号:
19590225
负责人:
WATANABE Tatsuo
金额:
$2.75万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2008
中文摘要
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英文摘要
本研究では、心房性ナトリウム利尿ペプチド(ANP)が脳内の"どこ"で"どの様"に発熱抑制に働くのかについてin vivoの実験系を用いて詳細に検討した。その結果、視床下部のANPによる発熱抑制と発熱時の視床下部でのANPやC-Type NP (CNP)さらにはインターロイキン1のmRNA発現を見いだした。ANP やCNP は視床下部内の受容体に作用して、発熱のメデイエーターの産生を抑制することで発熱を抑制するものと推察される。
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発熱研究の今昔日本臨床体温研究会
发热研究的前世今生日本临床体温研究会
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[上木史織, 渡邊達生, 渡邊達生]
通讯作者:
渡邊達生
ショウガの成分であるgingerolは代謝を低下させて低体温を引き起こす
生姜的成分姜辣素会减慢新陈代谢并导致体温过低。
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[上木史織, 渡邊達生]
通讯作者:
渡邊達生
ショウガの辛味成分であるgingerol の深部体温に及ぼす影響
生姜的辛辣成分姜辣素对核心体温的影响
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[上木史織, 渡邊達生]
通讯作者:
渡邊達生
慢性ストレスによる皮膚バリア機能低下に及ぼす緑の香りの抑制効果
绿色香味对慢性压力引起的皮肤屏障功能下降的抑制作用
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[伊藤愛, 上木史織, 渡邊達生]
通讯作者:
渡邊達生
"Green odor" inhalation reduces the skin-barrier disruption induced by chronic restraint stress in rats : physiological and histological examinations
吸入“绿色气味”可减少大鼠慢性束缚应激引起的皮肤屏障破坏:生理和组织学检查
DOI:
--
发表时间:
2007
期刊:
Chemical Senses 32(6)
影响因子:
--
作者:
[Fukada, M., Kaidoh, T., Ito, A., Yano, T.,Hayashibara, C., and Watanabe, T.]
通讯作者:
T.
共 9 条
Activities of thermosensitive TRP channels of foods having body-warming, body-chiling or cooling nature and effects on body temperature
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批准号:24580194
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.58万
-
财政年份:2012
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负责人:WATANABE Tatsuo
-
依托单位:
Chronic stress and depressive disorder : Research on preventive effect of odorant and its mechanism
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批准号:21590255
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.08万
-
财政年份:2009
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负责人:WATANABE Tatsuo
-
依托单位:
Investigation on atrial natriuretic peptide as an endogenous antipyretic
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批准号:17590204
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.24万
-
财政年份:2005
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负责人:WATANABE Tatsuo
-
依托单位:
Epidemiological studies of the relationships between periodontal diseases and systemic health
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批准号:17209066
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项目类别:Grant-in-Aid for Scientific Research (A)
-
资助金额:$31.78万
-
财政年份:2005
-
负责人:WATANABE Tatsuo
-
依托单位:
Title of project : Mechanisms underlying angiotensin II-stimulated production of proinflammatory cytokines : Are transcription factors involved?
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批准号:15590209
-
项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.24万
-
财政年份:2003
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负责人:WATANABE Tatsuo
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依托单位:
Measurement of changes of pungency-related compounds in pepper under cooking and development of stabilization method
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批准号:15500544
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.86万
-
财政年份:2003
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负责人:WATANABE Tatsuo
-
依托单位:
Studies on the involvement of intrahypothalamic angiotensin type 2 receptors in the development of fever in rats
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批准号:13470012
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$9.41万
-
财政年份:2001
-
负责人:WATANABE Tatsuo
-
依托单位:
Mechanism and prevention of periodontal pocket formation
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批准号:13470450
-
项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.02万
-
财政年份:2001
-
负责人:WATANABE Tatsuo
-
依托单位:
Intrahypothalamic secretion of angiotensin II in response to immunological or non-immunological stress in rats : a microdialysis study
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批准号:11670070
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.3万
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财政年份:1999
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负责人:WATANABE Tatsuo
-
依托单位:
Role of angiotensin II type 2 receptors in the development of stress-induced hyperthermia in mouse : a knockout mouse study
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批准号:09670071
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.05万
-
财政年份:1997
-
负责人:WATANABE Tatsuo
-
依托单位:
THE EFFECT OF MECHANICAL STRESS ON CELLS ISOLATED FROM GINGIVA
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批准号:09470470
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$9.47万
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财政年份:1997
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负责人:WATANABE Tatsuo
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依托单位:
Behavior management for mentally disabled dental patients with painless Local anesthesia.
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批准号:08672400
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.22万
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财政年份:1996
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负责人:WATANABE Tatsuo
-
依托单位:
Interleukin-1 production in the brain of febile and stress tolerant rabbits
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批准号:06670084
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项目类别:Grant-in-Aid for General Scientific Research (C)
-
资助金额:$1.41万
-
财政年份:1994
-
负责人:WATANABE Tatsuo
-
依托单位:
Response of human gingival microvascular endothelial cells to mechanical stress
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批准号:05404071
-
项目类别:Grant-in-Aid for General Scientific Research (A)
-
资助金额:$11.52万
-
财政年份:1993
-
负责人:WATANABE Tatsuo
-
依托单位:
Criteria for tooth extraction in periodontitis
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批准号:02454471
-
项目类别:Grant-in-Aid for General Scientific Research (B)
-
资助金额:$4.42万
-
财政年份:1990
-
负责人:WATANABE Tatsuo
-
依托单位:
Research of Public Health ot Prevent Periodontal Disease
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批准号:60480449
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项目类别:Grant-in-Aid for General Scientific Research (B)
-
资助金额:$4.03万
-
财政年份:1985
-
负责人:WATANABE Tatsuo
-
依托单位:
海外基金