课题基金 / 基金详情

Research on substance P receptor as a novel target for antidepressant therapy using neuroimaging techniques

Research on substance P receptor as a novel target for antidepressant therapy using neuroimaging techniques
利用神经影像技术研究 P 物质受体作为抗抑郁治疗的新靶点
批准号:
19590261
负责人:
SUZUKI Hidenori
金额:
$2.83万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2009

项目摘要

项目成果

SUZUKI Hidenori的其他基金

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中文摘要
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英文摘要
NK-1 receptors in the human brain were visualized and quantified using ^<18>F-FE-SPA-RQ with PET. The prefrontal and the limbic cortices, the regions responsible for the depression and the anxiety disorders, expressed substantial amount of NK-1 receptors. An fMRI study revealed neural substrates influenced by an antidepressant during the cognitive task performance. The combined application of both noninvasive neuroimaging techniques could be of great utility for development and evaluation of drugs to treat psychiatric disorders.
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会议论文
Quantitative analysis of NK1 receptor in the human brain using PET with 18F-FE-SPA-RQ.
使用 PET 和 18F-FE-SPA-RQ 对人脑中的 NK1 受体进行定量分析。
DOI: --
发表时间: 2008
期刊: J Nucl Med 49
影响因子: --
作者: [Okumura M, Arakawa R, Ito H, Seki C, Takahashi H, Takano H, Haneda E, Nakao R, Suzuki H, Suzuki K, Okubo Y, Suhara T]
通讯作者: Suhara T
Prenatal dexamethasone exposure affects anxiety-like behavior and neuroendocrine systems in an age-dependent manner
产前地塞米松暴露以年龄依赖性方式影响焦虑样行为和神经内分泌系统
DOI: --
发表时间: 2008
期刊: Neurosci. Res. 60
影响因子: --
作者: [Nagano, M.]
通讯作者: M.
クルグス診療科(4)基礎医学第4章
库尔古斯临床科(四)基础医学第四章
DOI: --
发表时间: 2008
期刊:
影响因子: --
作者: [Haneda, E., 鈴木秀典]
通讯作者: 鈴木秀典
Chronic SSRI changes the maturation state of dentate granule cells.
慢性 SSRI 会改变齿状颗粒细胞的成熟状态。
DOI: --
发表时间: 2008
期刊:
影响因子: --
作者: [Kobayashi K, Ikeda Y, Sakai A, Suzuki H]
通讯作者: Suzuki H
31
    Development of novel therapeutics for intractable neuropathic pain based on target protector RNA modulating HCN channel function
    • 批准号:
      20K09232
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.75万
    • 财政年份:
      2020
    • 负责人:
      SUZUKI Hidenori
    • 依托单位:
    Treatment of chronic pain utilizing GABAergic neuron derived from iPS
    • 批准号:
      17K10932
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.83万
    • 财政年份:
      2017
    • 负责人:
      SUZUKI Hidenori
    • 依托单位:
    Clarification of mechanisms of aneurysmal growth and rupture by quantification of 3D-domain hemodynamic irregularity
    • 批准号:
      17K10825
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $3.0万
    • 财政年份:
      2017
    • 负责人:
      SUZUKI Hidenori
    • 依托单位:
    Development of curative treatment against neuropathic pain through comprehensive functional analysis of human long non-coding RNAs
    • 批准号:
      16H05461
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $11.07万
    • 财政年份:
      2016
    • 负责人:
      SUZUKI Hidenori
    • 依托单位: