Development of the treatment of patients with chronic spinal cord injury using operating the cell attachment factors.
Development of the treatment of patients with chronic spinal cord injury using operating the cell attachment factors.
批准号:
20791045
负责人:
SUZUKI Hidenori
金额:
$2.75万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010
中文摘要
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英文摘要
We substituted damaged spinal cord in rats with chronic spinal cord injury for Collagen Filaments (CF). In addition, we impregnated with a Compound A which effected on the cell cycles and stimulated the repairs of tissues. In our vitro study, Compound A acted on the neural cells to promote mature differentiations. However, in vivo study, Compound A effected mainly on the Fibroblasts. So surroundings fibroblasts migrated across to the damaged spinal cord. In results, enough functional recovery were not shown in rats with chronic spinal cord injury. We think that additional ideas were necessary that genetically modified drugs etc effecting on neural cells specificity.
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脊髄損傷運動完全麻痺症例での治療経過の検討
脊髓损伤导致完全运动麻痹病例治疗过程的检查
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[鈴木秀典, 田口敏彦, 加藤圭彦, 國司善彦, 片岡秀雄, 寒竹司, 今城靖明, 富永俊克]
通讯作者:
富永俊克
コラーゲンフィラメントを用いた脊髄再生の試み~障害脊髄部における局所環境の改善~
利用胶原丝进行脊髓再生的尝试 - 改善受损脊髓的局部环境 -
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[鈴木秀典, 田口敏彦, 加藤圭彦, 片岡秀雄, 寒竹司, 屋良貴宏, 加藤秀豊, 守屋淳司, 好井覚]
通讯作者:
好井覚
Transplantation of neurospheres derived from bone marrow stromal cells promotes neurological recovery in rats with spinal cord injury
骨髓基质细胞神经球移植促进脊髓损伤大鼠神经功能恢复
DOI:
--
发表时间:
2011
期刊:
Medical molecular morphology
影响因子:
1.8
作者:
[Hidenori Suzuki, Toshihiko Taguchi, Yoshihiko Kato, et al.(他 6名)]
通讯作者:
et al.(他 6名)
Long tract reconstruction transected spinal cord gap using artificial collagen-filament scaffold
使用人工胶原丝支架进行长束重建横断脊髓间隙
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[鈴木秀典, 田口敏彦, 加藤圭彦, 片岡秀雄, 寒竹司, 屋良貴宏, 加藤秀豊, 守屋淳司, 好井覚, 鈴木秀典, Hidenori Suzuki]
通讯作者:
Hidenori Suzuki
脊髄損傷
脊髓损伤
DOI:
--
发表时间:
2012
期刊:
medicina
影响因子:
--
作者:
[金子慎二郎, 塩田匡宣, 臼井宏, 中村雅也, 戸山芳昭, 松本守雄]
通讯作者:
松本守雄
共 25 条
Development of novel therapeutics for intractable neuropathic pain based on target protector RNA modulating HCN channel function
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批准号:20K09232
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.75万
-
财政年份:2020
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负责人:SUZUKI Hidenori
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依托单位:
Treatment of chronic pain utilizing GABAergic neuron derived from iPS
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批准号:17K10932
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.83万
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财政年份:2017
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负责人:SUZUKI Hidenori
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依托单位:
Clarification of mechanisms of aneurysmal growth and rupture by quantification of 3D-domain hemodynamic irregularity
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批准号:17K10825
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.0万
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财政年份:2017
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负责人:SUZUKI Hidenori
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依托单位:
Development of curative treatment against neuropathic pain through comprehensive functional analysis of human long non-coding RNAs
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批准号:16H05461
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.07万
-
财政年份:2016
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负责人:SUZUKI Hidenori
-
依托单位:
Cure development by FDG-PET/CT and antiagent sensitivity in intractable head and neck squamous cell carcinoma
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批准号:16K11253
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.0万
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财政年份:2016
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负责人:SUZUKI Hidenori
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依托单位:
Cure development by FDG-PET and antiagent sensitivity in head and neck cancer
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批准号:24791821
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.5万
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财政年份:2012
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负责人:SUZUKI Hidenori
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依托单位:
Reconstruction of spinal cord function using collagen filaments
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批准号:23791647
-
项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.75万
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财政年份:2011
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负责人:SUZUKI Hidenori
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依托单位:
Elucidation of pathogenesis and new treatment for brain injury after subarachnoid hemorrhage
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批准号:22591584
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.83万
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财政年份:2010
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负责人:SUZUKI Hidenori
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依托单位:
Research on serotonergic neurons projecting to the prefrontal cortex as a target of drug development against psychiatric disorders
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批准号:22590249
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.91万
-
财政年份:2010
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负责人:SUZUKI Hidenori
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依托单位:
Cure development of anticancer agent sensitivity and the cancer stem cell in head and neck cancer
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批准号:21791660
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.75万
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财政年份:2009
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负责人:SUZUKI Hidenori
-
依托单位:
Research on substance P receptor as a novel target for antidepressant therapy using neuroimaging techniques
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批准号:19590261
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.83万
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财政年份:2007
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负责人:SUZUKI Hidenori
-
依托单位:
Ultrastructural Research of Platelet Raft
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批准号:17591022
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.24万
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财政年份:2005
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负责人:SUZUKI Hidenori
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依托单位:
A study on tachykininergic neurotransmission in the primate central nervous system aimed at developing novel drugs against mood disorders
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批准号:16590208
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.05万
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财政年份:2004
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负责人:SUZUKI Hidenori
-
依托单位:
Research for Intrinsic Regulation against Cerebral Vasospasm and Ischemia after Aneurysmal Subarachnoid Hemorrhage
-
批准号:15591518
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.18万
-
财政年份:2003
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负责人:SUZUKI Hidenori
-
依托单位:
Immunocytochemical Study on the Redistribution of Signal Molecules in Human Platelet Adherent to Extracellular Matrices
-
批准号:11671021
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.3万
-
财政年份:1999
-
负责人:SUZUKI Hidenori
-
依托单位:
A study of GDNF as a therapeutic drug for neuropathic pain
-
批准号:11672282
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.92万
-
财政年份:1999
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负责人:SUZUKI Hidenori
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依托单位:
Functional analyses of glial cell line-derived neurotrophic factor family
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批准号:09670109
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.66万
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财政年份:1997
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负责人:SUZUKI Hidenori
-
依托单位:
Immunocytochemical Study on the Redistribution of alphallbbeta3 Integrin and Cytoskeleton adherent to collagen
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批准号:08671266
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.22万
-
财政年份:1996
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负责人:SUZUKI Hidenori
-
依托单位:
Immunocytochemical study on the association between alpha-granule membrane proteins and adhesive proteins during platelet activation.
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批准号:04671543
-
项目类别:Grant-in-Aid for General Scientific Research (C)
-
资助金额:$1.34万
-
财政年份:1992
-
负责人:SUZUKI Hidenori
-
依托单位: