Clarification of developing metabolic syndrome by using expressionanalysis of human visceral adipose tissue
Clarification of developing metabolic syndrome by using expressionanalysis of human visceral adipose tissue
批准号:
19591038
负责人:
HARA Kazuo
金额:
$2.91万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2008
中文摘要
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英文摘要
ヒト脂肪組織で、肥満で発現が亢進していることが報告されているレプチン、IL18遺伝子についてはBMIと正の相関を認め、逆に肥満で発現が低下するアディポネクチンはBMI と負の相関を認め、ヒト脂肪組織の発現解析によってメタボリックシンドロームの病態に関与する新たなアディポカインの同定に役立つ可能性が確認された。我々が新規2型糖尿病遺伝子として同定した遺伝子Xについて遺伝子多型と遺伝子発現が相関することを確認した。
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Frequency of the G/G genotype of resistin single nucleotide polymorphism at -420 appears to be increased in younger-onset type 2 diabetes.
在年轻发病的 2 型糖尿病中,-420 处抵抗素单核苷酸多态性的 G/G 基因型频率似乎有所增加。
DOI:
--
发表时间:
2007
期刊:
Diabetes 56
影响因子:
--
作者:
[Ochi, M., Osawa, H., Kadowaki, T. (13番目), Kasuga, M. (15番目), Makino, H. (16人中16番目), ほか11名]
通讯作者:
ほか11名
Construction of a prediction model for type 2 diabetes mellitus in the Japnese population based on 11 genes with strong evidence of the association.
基于 11 个有强有力证据证明相关性的基因,构建了日本人群 2 型糖尿病的预测模型。
DOI:
--
发表时间:
2008
期刊:
J Hum Genet 54
影响因子:
--
作者:
[Miyake K, Yang W, Hara K et al.]
通讯作者:
Hara K et al.
Ito C,Shojima N et al.Variations in theHHEXgene are associated with increased risk of type 2 diabetes in the Japanesepopulation
Ito C, Shojima N et al. HHEX 基因的变异与日本人群患 2 型糖尿病的风险增加有关
DOI:
--
发表时间:
2007
期刊:
Diabetologia 50(12)
影响因子:
--
作者:
[Horikoshi M, Hara K]
通讯作者:
Hara K
DOI:
10.1536/ihj.49.313
发表时间:
2008-05
期刊:
International heart journal
影响因子:
1.5
作者:
[Guoqin Wang;Masafumi Watanabe;Y. Imai;K. Hara;I. Manabe;K. Maemura;M. Horikoshi;T. Kohro;E. Amiya;T. Sugiyama;T. Fujita;T. Kadowaki;T. Yamazaki;R. Nagai]
通讯作者:
Guoqin Wang;Masafumi Watanabe;Y. Imai;K. Hara;I. Manabe;K. Maemura;M. Horikoshi;T. Kohro;E. Amiya;T. Sugiyama;T. Fujita;T. Kadowaki;T. Yamazaki;R. Nagai
Ito C, Shojima N, Genomic Disorders 2008
Ito C,Shojima N,基因组疾病 2008
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[Horikoshi M, Hara K,]
通讯作者:
Hara K,
共 14 条
Documentary film about Asbestos damage in Sennan area, Osaka
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批准号:25370194
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.16万
-
财政年份:2013
-
负责人:HARA Kazuo
-
依托单位:
Clarification of genetic architecture of type 2 diabetes using expression analysis
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批准号:21591124
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.08万
-
财政年份:2009
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负责人:HARA Kazuo
-
依托单位:
Parsing with Coordinate Structure Analysis based on Sequence Alignment
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批准号:21700170
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.75万
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财政年份:2009
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负责人:HARA Kazuo
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依托单位:
A Fluid Dynamic Study of Gas Bearing for High Speed Mini-Scale Turbo Machinery
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批准号:16206021
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$31.37万
-
财政年份:2004
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负责人:HARA Kazuo
-
依托单位:
Identification of type 2 diabetes susceptibility genes in the Japanese population by linkage disequilibrium mapping in the chromosomal regions harboring type 2 diabetes susceptibility genes
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批准号:15310138
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$7.49万
-
财政年份:2003
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负责人:HARA Kazuo
-
依托单位:
EDUGATIONAL-METHODOLOGICAL ANALYSES OF FACULTY DEVELOPMENT ACTIVITIES
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批准号:08610280
-
项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$0.9万
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财政年份:1996
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负责人:HARA Kazuo
-
依托单位:
Effects of Coriolis force on Complex Turbulent Flow Field in Compressor Rotor
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批准号:07650210
-
项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.66万
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财政年份:1995
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负责人:HARA Kazuo
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依托单位:
Planning and Practice of Faculty Development Program for University Teachers.
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批准号:63450040
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$2.82万
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财政年份:1988
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负责人:HARA Kazuo
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依托单位:
海外基金