Clinical application of anti-CADM-140 antibodies detected inpatients with dermatomyositis
Clinical application of anti-CADM-140 antibodies detected inpatients with dermatomyositis
批准号:
19591178
负责人:
SATO Shinji
金额:
$2.91万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2008
中文摘要
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英文摘要
臨床的に筋炎症状に乏しい皮膚筋炎(C-ADM)に見出された抗CADM-140抗体の対応抗原がMDA5(Melanoma Differentiation-Associated Gene 5)であることを明らかにし, 同抗体測定ELISAを確立した. 同抗体陽性例は, 急速進行性間質性肺炎(RP-ILD)を有意に併発していた. 今回の研究成果は, 予後不良のRP-ILD併発C-ADMの早期診断に有用で, 予後の改善につながることが期待される.
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皮膚筋炎と抗CADM-140抗体
皮肌炎和抗 CADM-140 抗体
DOI:
--
发表时间:
2008
期刊:
リウマチ科 40
影响因子:
--
作者:
[Shinji Sato, et al, 佐藤慎二]
通讯作者:
佐藤慎二
Classification of dermatomyositis using myositis-specific autoantibodies and newly found autoantibodies in patients with dermatomyositis
使用肌炎特异性自身抗体和皮肌炎患者新发现的自身抗体对皮肌炎进行分类
DOI:
--
发表时间:
2007
期刊:
影响因子:
--
作者:
[Sato S, Hoshino K, Satoh T, Yamaguchi Y, Hirakata M, Kuwana M]
通讯作者:
Kuwana M
皮膚筋炎に見出された抗CADM-140抗体の病因的・臨床的意義
皮肌炎中发现的抗 CADM-140 抗体的病因学和临床意义
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[佐藤慎二, 他]
通讯作者:
他
MDA5 (Melanoma-Differentiation Associated Gene 5) as anantigen recognized by anti-CADM-140 antibody in patients with clinically amyopathic dermatomyositis.
MDA5(黑色素瘤分化相关基因 5)作为临床无肌病性皮肌炎患者的抗 CADM-140 抗体识别的抗原。
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[Shinji Sato, et al]
通讯作者:
et al
筋炎特異および関連自己抗体を用いた皮膚筋炎の病型分類の検討
使用肌炎特异性和相关自身抗体检查皮肌炎的病理分类
DOI:
--
发表时间:
2007
期刊:
影响因子:
--
作者:
[佐藤慎二, 星野香菜, 佐藤隆司, 山口由衣, 諏訪昭, 平形道人, 桑名正隆]
通讯作者:
桑名正隆
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