Development of Radiation-Therapy Planning Using FDG-PET/CT Fused Imaging

使用 FDG-PET/CT 融合成像制定放射治疗计划

• 批准号: 19591461
• 负责人: MURAKAMI Ryuji
• 金额: $ 2.16万
• 依托单位: Kumamoto University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2007
• 资助国家: 日本
• 起止时间: 2007 至 2008
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19591461/
• 关键词: 放射線治療学; 放射線治療計画; ポジトロン断層撮像(PET); がん; 放射線治療; 画像診断; 機能画像; 画像解析; PET; 癌; 臨床; 放射線; 画像; 解析・評価

模擬病巣およびPET用放射性薬剤(FDG)を用いた基礎的研究において、描出能は病巣の大きさおよび周囲RIカウントの影響を受けた。臨床評価における小病巣の過小評価および周囲炎症による過大評価が基礎的に明らかとなり、腫瘍-非腫瘍境界の閾値は症例毎に定める必要性が示唆された。FDG-PETを臨床応用したリンパ節転移の診断では、小径のリンパ節における閾値は低値を要した。位置情報を加味した三次元的腫瘍体積評価に関して、通常の臨床情報にPET-CTを追加することによる観察者間での差異の軽減が明らかとなった。

PET was used as a model of radiation therapy (FDG). Based on the results of the study, it was shown that there was a significant difference in the number of patients who were affected by the disease. The results showed that there was a significant difference between the two groups in the treatment of RI disease. In the hospital, patients with minor illnesses, patients with severe inflammation, patients with severe diseases, patients with chronic diseases, patients with mild diseases, patients with minor diseases, patients with chronic inflammation, patients with chronic diseases, patients with severe diseases, patients with severe diseases, patients with chronic diseases, patients with mild illness, patients with minor diseases, patients with severe inflammation, patients with severe diseases, patients with chronic diseases, patients with chronic diseases, patients with mild illness, patients with mild illness, patients with minor diseases, patients with severe inflammation, patients with severe inflammation, patients with severe acute respiratory syndrome, patients with severe FDG-PET said that the bed would be cut off, the path would be broken and the path would be low. The location of the three-dimensional situation is different, usually the bed situation is called PET-CT, and the number of people who are aware of the situation is different.

项目成果

Diffusion-weighted MR imaging of gliomas:Role in their diagnosis and treatment

胶质瘤的弥散加权磁共振成像：在其诊断和治疗中的作用

• 发表时间: 2007
• 作者: Okumura K;Shiomi H;et. al;Ryuji Murakami
• 通讯作者: Ryuji Murakami

Cone-Beam CTを用いた放射線治療計画に関する臨床的検討

锥束CT放射治疗计划的临床研究

• 发表时间: 2008
• 作者: 村上龍次;中口裕二;丸山雅人;筧清孝;坂部大介;村山淳一;東家亮;斉藤哲雄;坂本隆吏;大屋夏生;荒木不次男
• 通讯作者: 荒木不次男

Impact of FDG-PET/CT fused imaging on tumor volume assessment of head-and-neck squamous cell carcinoma: Intermethod and interobserver variations

• DOI: 10.1080/02841850802027034
• 发表时间: 2008-01-01
• 期刊: ACTA RADIOLOGICA
• 影响因子: 1.3
• 作者: Murakami, R.;Uozumi, H.;Yamashita, Y.
• 通讯作者: Yamashita, Y.

Impact of FDG-PET/CT imaging on nodal staging for head-and-neck squamous cell carcinoma

• DOI: 10.1016/j.ijrobp.2006.12.032
• 发表时间: 2007-06-01
• 期刊: INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
• 影响因子: 7
• 作者: Murakami, Ryuji;Uozumi, Hideaki;Yamashita, Yasuyuki
• 通讯作者: Yamashita, Yasuyuki

Grading Astrocytic Tumors by Using Apparent Diffusion Coefficient Parameters: Superiority of a One- versus Two-Parameter Pilot Method

• DOI: 10.1148/radiol.2513080899
• 发表时间: 2009-06-01
• 期刊: RADIOLOGY
• 影响因子: 19.7
• 作者: Murakami, Ryuji;Hirai, Toshinori;Yamashita, Yasuyuki
• 通讯作者: Yamashita, Yasuyuki