The exhaustive research of prognostic factor for chronic heart failure

慢性心力衰竭预后因素的详尽研究

• 批准号: 19790523
• 负责人: HIRASHIKI Akihiro
• 金额: $ 2.4万
• 依托单位: Nagoya University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2007
• 资助国家: 日本
• 起止时间: 2007 至 2008
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19790523/
• 关键词: 慢性心不全; 心筋特性; 予後予測因子; 心機能; ドブタミン負荷; ペーシング負荷

慢性心不全に対し、病態と予後との関連解析を行い、新しい病態生理の発見や予後指標の開発を目的として平成20年度の研究を進めた。2007年、11月に行われたAHA Scientific Sessions 2007において、ドブタミン誘発性機械的交互脈は予後不良因子であることを初めて報告した。また慢性心不全の一病態である肥大型心筋症では、ミトコンドリア機能は障害されており、その障害が左室収縮および弛緩予備能の低下に関与していることを報告した。

Chronic heart failure (CHD), chronic heart disease (CHD), chronic heart failure (CHD), chronic heart insufficiency (CHD), chronic heart insufficiency (CHD), chronic heart disease (CHD), chronic heart insufficiency (CHD), chronic heart disease (CHD), chronic heart failure (CHD), chronic heart failure (CHD), chronic heart disease (CH In 2007 and November, AHA Scientific Sessions 2007 was launched, and the interaction between sexual machinery and machinery was reported. In the case of chronic heart insufficiency, the symptoms of hypertrophic cardiomyopathy, hypertrophic cardiomyopathy, chronic heart failure, chronic heart insufficiency, chronic heart insufficiency, hypertrophic heart disease, chronic heart insufficiency, chronic heart insufficiency, hypertrophic heart disease, chronic heart insufficiency, chronic heart insufficiency, hypertrophic heart disease, chronic heart insufficiency, chronic heart insufficiency, hypertrophy, hypertrophy, hypertrophy,

项目成果

Relation of peak VO2 to myocardial contractile reserve measured by dobutamine stress testing in patients with idiopathic dilated cardiomyopathy

特发性扩张型心肌病患者多巴酚丁胺负荷试验测得的峰值摄氧量与心肌收缩储备的关系

• 发表时间: 2009
• 作者: Noda A;Izawa H;Asano H;Nakata S;Hirashiki A;Murase Y;Iino S;Nagata K;Murohara T;Koike Y;Yokota M.;Hirashiki A;Okumura T
• 通讯作者: Okumura T

Preservation of Myocardial Contractile Reserve in Nonischemic Dilated Cardiomyopathy Patients with Sleep-Disordered Breathing

睡眠呼吸障碍非缺血性扩张型心肌病患者心肌收缩储备的保存

• 发表时间: 2009
• 作者: Noda A;Izawa H;Asano H;Nakata S;Hirashiki A;Murase Y;Iino S;Nagata K;Murohara T;Koike Y;Yokota M.;Hirashiki A;Okumura T;Hirashiki A;Hirashiki A
• 通讯作者: Hirashiki A

Dobutamine Stress Testing as a Diagnostic Tool for Evaluation of Myocardial Contractile Reserve in Asymptomatic or Mildly Symptomatic Patients With Dilated Cardiomyopathy

• DOI: 10.1016/j.jcmg.2008.04.012
• 发表时间: 2008-11-01
• 期刊: JACC-CARDIOVASCULAR IMAGING
• 影响因子: 14
• 作者: Kobayashi, Masakazu;Izawa, Hideo;Yokota, Mitsuhiro
• 通讯作者: Yokota, Mitsuhiro

Increased 99mTc-Sestamibi Washout Reflects Impaired Myocardial Contractile Reserve and Prolonged Relaxation in Patients with Nonobstructive Hypertrophic Cardiomyopathy

99mTc-Sestamibi 冲洗增加反映了非梗阻性肥厚型心肌病患者心肌收缩储备受损和长时间舒张

• 发表时间: 2008
• 作者: Noda A;Izawa H;Asano H;Nakata S;Hirashiki A;Murase Y;Iino S;Nagata K;Murohara T;Koike Y;Yokota M.;Hirashiki A;Okumura T;Hirashiki A;Hirashiki A;Okumura T;Hirashiki A;Ohshima K;Unno K
• 通讯作者: Unno K

Prognostic Value of Dobutamine-Induced Mechanical in Patients With Mildly to Moderately Idiopathic Dilated Cardiomyopathy in sinus rhythm.

多巴酚丁胺诱导的机械对窦性心律轻至中度特发性扩张型心肌病患者的预后价值。

• 发表时间: 2008
• 作者: Noda A;Izawa H;Asano H;Nakata S;Hirashiki A;Murase Y;Iino S;Nagata K;Murohara T;Koike Y;Yokota M.;Hirashiki A;Okumura T;Hirashiki A;Hirashiki A;Okumura T;Hirashiki A;Ohshima K;Unno K;Unno K;Kobayashi M;Kobayashi M;平敷安希博;Hirashiki A
• 通讯作者: Hirashiki A