Development of Asymmetric Supramolecular Catalysts with Antibodies and Transition Metal Complexes

为了利用其抗原结合位点构建特异性反应场，制备了一些能与有机金属配合物高特异性、高亲和力结合的单克隆抗体。通过将金属络合物掺入单克隆抗体的结合位点来开发独特的功能。还成功地制备了过渡金属配合物立体异构体或有机化合物对映体的单克隆抗体。

Some monoclonal antibodies which can bind organic metal complexes with high specificity and high affinity were prepared in order to construct a specific reaction field utilizing their antigen-binding sites. Unique functions were developed by the incorporation of metal complexes into the binding site of monoclonal antibodies. Monoclonal antibodies for stereoisomers of transition metal complexes or enantiomers of organic compounds were also prepared successfully.