Study for target molecules of poIyphenoIs to evaluate their functions and safety.
Study for target molecules of poIyphenoIs to evaluate their functions and safety.
批准号:
19688007
负责人:
KAWAI Yoshichika
金额:
$15.23万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (A)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2010
中文摘要
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英文摘要
To investigate the molecular mechanism for the functions and safety of polyphenols and to identify their molecular targets, we developed novel monoclonal antibodies that specifically recognize quercetin or epicatechin gallate. Using these antibodies, we have identified macrophage cells in human aorta as the specific target of these polyphenols.
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DOI:
10.1016/j.bbrc.2008.07.086
发表时间:
2008-09-26
期刊:
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
影响因子:
3.1
作者:
[Kawai, Yoshichika, Tanaka, Hiroko, Terao, Junji]
通讯作者:
Terao, Junji
Immunochemical characterization of dietary f-avonoid metabolites in aorta: Implication in the anti-atherosclerosis effects
主动脉中膳食类黄酮代谢物的免疫化学特征:抗动脉粥样硬化作用的意义
DOI:
--
发表时间:
2007
期刊:
影响因子:
--
作者:
[河合慶親, 寺尾純二, 河合慶親ら, Yoshichika Kawai]
通讯作者:
Yoshichika Kawai
Immunochemical characterization of flavonoid metabolites in aorta:implication in the anti-atherosclerotic effect
主动脉中类黄酮代谢物的免疫化学特征:抗动脉粥样硬化作用的意义
DOI:
--
发表时间:
2007
期刊:
影响因子:
--
作者:
[河合慶親, 寺尾純二, 河合慶親ら, Yoshichika Kawai, 伊東 久仁, 河合慶親]
通讯作者:
河合慶親
DOI:
10.1271/bbb.80516
发表时间:
2009-03-01
期刊:
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
影响因子:
1.6
作者:
[Kawai, Yoshichika, Saito, Satomi, Terao, Junji]
通讯作者:
Terao, Junji
DOI:
10.1021/tx8000835
发表时间:
2008-08-01
期刊:
CHEMICAL RESEARCH IN TOXICOLOGY
影响因子:
4.1
作者:
[Shiba, Yuko, Kinoshita, Takashi, Kawai, Yoshichika]
通讯作者:
Kawai, Yoshichika
共 12 条
Study on biological activity of food-derived nucleic acids in intestinal immune system
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批准号:15K14730
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.5万
-
财政年份:2015
-
负责人:KAWAI Yoshichika
-
依托单位:
Study on the interaction between target cells and polyphenol conjugates underlying the molecular mechanism of their biological activity
-
批准号:26292069
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$10.73万
-
财政年份:2014
-
负责人:KAWAI Yoshichika
-
依托单位:
Evaluation of inflammatory responses by mitochondrial DNA adducts
-
批准号:25660103
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.58万
-
财政年份:2013
-
负责人:KAWAI Yoshichika
-
依托单位:
Screening of food factors that target the quality control system of mitochondria
-
批准号:23658118
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.41万
-
财政年份:2011
-
负责人:KAWAI Yoshichika
-
依托单位:
海外基金