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Utilization of spontaneous melanoma mice for finding biomarkers

Utilization of spontaneous melanoma mice for finding biomarkers
利用自发性黑色素瘤小鼠寻找生物标志物
批准号:
19700371
负责人:
KAWAMOTO Yoshiyuki
金额:
$2.37万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2009

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中文摘要
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英文摘要
RET-transgenic mice, which develop malignant melanoma, are useful for finding biomarkers which express in the serum or urine correlated with tumor progression and/or metastasis. We found that chemokin (C-X-C motif) ligand, CXCL10 and CXCL16 are significantly increased in serum of RET-transgenic mice which has malignant tumor. Our findings suggest that these proteins can be candidates for new biomarkers of melanoma.
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会议论文
チオール反応性化合物によるアポトーシス誘導とシグナル伝達機序
硫醇反应性化合物的细胞凋亡诱导和信号转导机制
DOI: --
发表时间: 2009
期刊:
影响因子: --
作者: [Hossain K, Kawamoto Y, Hamada M, Akh, AA, Yanagishita T, Hoque MA, Tsuboi H, Kato M, Nakashima I., 川本善之]
通讯作者: 川本善之
1, 4-butanediyl-bismethanethiosulfonate (BMTS) induces apoptosis through reactive oxygen species-mediated mechanism.
1, 4-丁二基-双甲烷硫代磺酸盐 (BMTS) 通过活性氧介导的机制诱导细胞凋亡。
DOI: --
发表时间: 2009
期刊: J Cell Biochem. 108(5)
影响因子: --
作者: [Hossain K, Kawamoto Y, Hamada M, Akh, AA, Yanagishita T, Hoque MA, Tsuboi H, Kato M, Nakashima I.]
通讯作者: Nakashima I.
Analysis of anti-tumor activity of interleukin-9 in melanoma models.
  • 批准号:
    25430096
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $3.49万
  • 财政年份:
    2013
  • 负责人:
    KAWAMOTO Yoshiyuki
  • 依托单位:
Exploration of disease-related proteins from spontaneous model of melanoma by proteomics analysis
  • 批准号:
    22700457
  • 项目类别:
    Grant-in-Aid for Young Scientists (B)
  • 资助金额:
    $2.5万
  • 财政年份:
    2010
  • 负责人:
    KAWAMOTO Yoshiyuki
  • 依托单位:
海外基金