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Functional analysis of phospholipase C-zeta-deficient mouse

Functional analysis of phospholipase C-zeta-deficient mouse
磷脂酶 C-zeta 缺陷小鼠的功能分析
批准号:
19790170
负责人:
ITO Masahiko
金额:
$2.45万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2009

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项目成果

ITO Masahiko的其他基金

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中文摘要
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英文摘要
In mammalian fertilization, Ca^<2+> oscillations are indispensable for egg- activation. Sperm specific isotype of phospholopase C (PLCZ1) is a strong candidate for egg-activating sperm factor. In this study, regulation of Ca^<2+> oscillations by PLCZ1 was examined about nuclear localization ability and Ca^<2+> oscillation inducing activity. Moreover, PLCZ1 deficient mice were analyzed and it was shown that PLCZ1 has a pivotal role for spermatogenesis as well as an egg activation.
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卵活性化精子因子候補ホスホリパーゼCゼータの核移行能の役割
卵子激活精子因子候选磷脂酶 C zeta 的核转位能力的作用
DOI: --
发表时间: 2007
期刊:
影响因子: --
作者: [Akiba L, Fukuda H, Yasuoka Y, Kawahara K, 伊藤 昌彦]
通讯作者: 伊藤 昌彦
Relationship between Nuclear sequestration of PLCzeta and termination of PLCzeta-induced Ca2+ oscillations in mouse eggs.
PLCzeta 的核隔离与小鼠卵中 PLCzeta 诱导的 Ca2 振荡终止之间的关系。
DOI: --
发表时间: 2008
期刊: Cell Calcium 44
影响因子: --
作者: [Masahiko Ito, Tomohide Shikano, Keiji Kuroda, Shunichi Miyazaki.]
通讯作者: Shunichi Miyazaki.
Difference in Ca^<2+> oscillation-inducing activity and nuclear translocation ability of PLCZ1, an egg-activating sperm factor candidate, among mouse, rat, human and medaka fish
小鼠、大鼠、人类和青鳉鱼中候选卵子激活精子因子 PLCZ1 的 Ca^<2> 振荡诱导活性和核转位能力的差异
DOI: --
发表时间: 2008
期刊: Biol. Reprod 78
影响因子: --
作者: [Masahiko Ito, et.al.]
通讯作者: et.al.
Analysis of negative feedback mechanism of phospholipase C-zeta, a egg-activating spermfactor candidate, overexpression
卵子激活精子因子候选物磷脂酶C-zeta过表达负反馈机制分析
DOI: --
发表时间: 2009
期刊:
影响因子: --
作者: [Aoyagi T, Yasuoka Y, ets, 伊藤昌彦]
通讯作者: 伊藤昌彦
7
    Research on the difference systems associated with multivariable elliptic hypergeometric functions with Weyl group symmetry
    Screening of novel host factors related to HCV lifecycle for developing useful drugs
    • 批准号:
      24659480
    • 项目类别:
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额:
      $2.41万
    • 财政年份:
      2012
    • 负责人:
      ITO Masahiko
    • 依托单位:
    Energy-saving vibration suppression control of the twin-drive geared system for speeding up the feeding axis of the presswork machine
    • 批准号:
      19560245
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.16万
    • 财政年份:
      2007
    • 负责人:
      ITO Masahiko
    • 依托单位:
    Research on the holonomic q difference systems associated with the Jackson integrals of Weyl group invariant
    • 批准号:
      17540037
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.28万
    • 财政年份:
      2005
    • 负责人:
      ITO Masahiko
    • 依托单位: